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c/tirzepatide·submitted 2 years ago by u/teodor_szabo

[Discussion] the SURMOUNT advice in here is 17 years out of date

Discussionbranch of 7 comments

Trying to settle this properly because the thread from last year went in circles. The claim: SURMOUNT matters. The counter-claim: it is measurement error. Both sides have been asserting it confidently for about 19 months without either producing anything. What would actually settle it is 17 people measuring the same…

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7 comments, started 2 years ago
u/dario_stanescu449 points·2 years ago·edited

the GIP side does different things than the GLP-1 side, that is the point

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u/thyroid_tangent-10 points·2 years ago

You have restated the marketing copy. What is the actual substance here.

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u/copay_card_cc1 point·2 years ago

week 22 on Mounjaro and the appetite profile is genuinely different from sema

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u/marta_dziedzic1 point·2 years ago

Is that on Mounjaro pens or research tirzepatide?

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u/nordic_pricing1 point·2 years ago

stalled on sema, tried tirz, and the curves were actually different shapes

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[removed]1 point·2 years ago

[removed by moderator]

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u/thyroid_tangent1 point·2 years ago

You have restated the marketing copy. What is the actual substance here.

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About c/tirzepatide

Tirzepatide-specific discussion: the dual-agonist pharmacology, the 2.5 → 15mg ladder, the appetite profile people describe as different from semaglutide, and the SURMOUNT/SURPASS trial programme. Comparisons with semaglutide are welcome as long as they are specific about dose equivalence being unknown.

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