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c/retatrutide·submitted 5 months ago by u/burned_once_twice

[Vendor] WXT order #4 — Germany, 13 days, no drama, receipts inside

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Long-ish post, sorry. tl;dr at the bottom. I have been tracking retatrutide against eGFR for 27 weeks because I could not find anyone who had. The correlation is weaker than I expected, which is itself mildly interesting given how confidently people link the two in here. Caveats up front: one person, one lab, one…

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7 comments, started 5 months ago
u/mateusz_mensah-24 points·5 months ago

Did you actually measure heart rate or is that a feeling?

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u/marit_laurent1 point·5 months ago

the weight curves are unusually steep, which makes predicting individual response harder

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u/burned_once_twiceOP1 point·5 months ago

Dose escalation on retatrutide is steeper and faster than on semaglutide. Do not assume the titration patterns transfer.

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u/marta_vanhecke1 point·5 months ago

Strongly agree. Heart rate escalation needs the actual data, not impressions.

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u/nikhil_lindqvist1 point·5 months ago

phase 2 numbers are not maintenance numbers, cite the trial

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u/careful_gradient_notes1 point·5 months ago·edited

triple agonism is retatrutide, do not generalise

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[removed]1 point·5 months ago

[removed by moderator]

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About c/retatrutide

Retatrutide: GIP/GLP-1/glucagon triple agonism, the TRIUMPH programme, and the fact that most people discussing it are handling research-grade material with no human-use approval anywhere. Dose-response, heart-rate signal, and the unusually steep phase-2 weight curves get argued about here weekly.

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