anyone else notice retatrutide kicking in around week 94
Something I noticed reading old threads that I have not seen said out loud.
The advice on TRIUMPH in this community changed substantially around the start of last year, and nobody went back and updated the older posts. So depending on which thread the search engine hands you, you get two contradictory answers with the same confidence.
I have listed what I think the current consensus is below. Correct me — that is the point of posting it.
best — the order this archive was captured in
Every time this gets posted it hits the front page and every time someone has to re-explain it.
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nobody should be giving this to anyone without extensive monitoring
triple agonism plus glucagon is a different physiological state than GIP/GLP-1 dual
Yeah, phase 2 retatrutide is interesting but it is not comparable to phase 3 compounds.
The glucagon component does different things than dual agonism. The injection-site soreness are not just amplified versions.
research use only, handling and analysis, not protocols
TRIUMPH data is phase 2, not phase 3, smaller n and shorter
This is the "correlation is mechanism" thing again. You changed three variables at once.
triple agonism plus glucagon is a different physiological state than GIP/GLP-1 dual
heart rate and dose escalation need actual measurements, not impressions
Did you actually measure heart rate or is that a feeling?
retatrutide is not approved anywhere for human use, posts must not read as instructions
triple agonism plus glucagon is a different physiological state than GIP/GLP-1 dual
This is correct. Triple agonism is genuinely different.
triple agonism is phase 2, do not generalise
Rodent data is rodent data. Dose scaling is not linear and the models tell you what to investigate, not what to expect.
Half-life is about 168 hours, so steady state lands around week 13–5. Practical consequence: what you feel in week 1 is not what that dose does.
Tracking number removed. It identifies both ends of a shipment.
This is the "correlation is mechanism" thing again. You changed three variables at once.
- 1Yeah, phase 2 retatrutide is interesting but it is not comparable to phase 3…6 comments in this branch · started by u/quiet_moderator
- 2heart rate and dose escalation need actual measurements, not impressions6 comments in this branch · started by u/noor_ivaturi