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c/retatrutide·submitted 1 year ago by u/lurker_for_years

someone explain glucagon to me like I have not read a paper in years

Trial Databranch of 7 comments

I have had 23 orders now and I keep a table, so here is the honest summary rather than a vibe. Material has been consistent. Communication has not. Shipping has varied by about 38 days on nominally the same lane, which matters more in summer than in February. The independent number came back 97.9% against a claimed…

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7 comments, started 1 year ago
u/hugo_pires83 points·1 year ago

the weight curves are unusually steep, which makes predicting individual response harder

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u/yannick_salinas66 points·1 year ago

Strongly agree. Heart rate escalation needs the actual data, not impressions.

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u/divya_bakken16 points·1 year ago

Sceptical. If this were true we would see it reflected in the data and we do not.

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u/signe_villalobos-2 points·1 year ago

triple agonism plus glucagon is a different physiological state than GIP/GLP-1 dual

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u/isabela_nilsen12 points·1 year ago

That is net peptide content, not purity. Different number, different meaning.

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About c/retatrutide

Retatrutide: GIP/GLP-1/glucagon triple agonism, the TRIUMPH programme, and the fact that most people discussing it are handling research-grade material with no human-use approval anywhere. Dose-response, heart-rate signal, and the unusually steep phase-2 weight curves get argued about here weekly.

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c/retatrutide rules
  1. Retatrutide is not approved anywhere for human use. Posts must not read as usage instructions.
  2. Phase 2 numbers are not maintenance numbers. Cite the trial and the dose arm.
  3. Heart-rate and dose-escalation reports need actual measurements, not impressions.
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