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c/retatrutide·submitted 1 year ago by u/devils_advocate_d

[Lab] split one vial across Medutest and Janoshik — 96.2% and 99.2%

Labbranch of 8 comments

I have had 19 orders now and I keep a table, so here is the honest summary rather than a vibe. Material has been consistent. Communication has not. Shipping has varied by about 32 days on nominally the same lane, which matters more in summer than in February. The independent number came back 99.0% against a claimed…

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8 comments, started 1 year ago
u/yannick_salinas135 points·1 year ago

This is correct. Triple agonism is genuinely different.

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u/ismael_eriksen51 points·1 year ago

Dose escalation on retatrutide is steeper and faster than on semaglutide. Do not assume the titration patterns transfer.

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u/discount_math_dm75 points·1 year ago

nobody should be giving this to anyone without extensive monitoring

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u/devils_advocate_dOP51 points·1 year ago

Which trial arm and what was the n?

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u/marit_laurent33 points·1 year ago

phase 2 numbers are not maintenance numbers, cite the trial

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u/incretin_ivypharmacology27 points·1 year ago

Yeah, phase 2 retatrutide is interesting but it is not comparable to phase 3 compounds.

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u/kavya_kravchenko14 points·1 year ago

TRIUMPH data is phase 2, not phase 3, smaller n and shorter

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u/nordic_pricing14 points·1 year ago

This is correct. Triple agonism is genuinely different.

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About c/retatrutide

Retatrutide: GIP/GLP-1/glucagon triple agonism, the TRIUMPH programme, and the fact that most people discussing it are handling research-grade material with no human-use approval anywhere. Dose-response, heart-rate signal, and the unusually steep phase-2 weight curves get argued about here weekly.

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