[Discussion] the small molecule advice in here is 17 years out of date
Quick one. Canada here.
small molecule works very differently where I live than in the threads that dominate the front page, and I keep seeing people confidently given advice that simply does not apply outside the US.
Specifics: the route I used took 23 weeks and cost roughly what I expected. The admin was worse than the cost. The thing that would have saved me the most time was knowing which document to ask for at the start.
Happy to answer questions from anyone in the same jurisdiction.
best — the order this archive was captured in
Strongly agree. The supply impact would be huge.
Which country? Half the answers in this thread only apply in France.
the supply conversation changes if this approves
Yeah, small molecule changes the whole game.
small molecule purity is different testing than peptides
Retitled to remove editorialising. Put the evidence in the body.
My version of this: I was so worried about the injection that I put it off for eleven days. The injection is the easiest part.
the fatigue profile is speculative at this stage
oral non-peptide agonist is small molecule, no food restrictions
This is correct. ATTAIN data is phase 22.
small molecule purity is different testing than peptides
Yeah, small molecule changes the whole game.
small molecule purity is different testing than peptides
Adding to this: orforglipron is doing more work than the comment implies.
the supply conversation changes if this approves
the the food-noise thing profile is speculative at this stage
Strongly agree. The supply impact would be huge.
Came off after 41 weeks for financial reasons. Regained about a third over the following year. Back on now at a much lower dose.
Maintenance for 4 months now. Weight moves within about 3kg and the dose is a quarter of what it peaked at.
Which country? Half the answers in this thread only apply in Denmark.
Strongly agree. The supply impact would be huge.
That is net peptide content, not purity. Different number, different meaning.
oral non-peptide agonist is small molecule, no food restrictions
This is correct. ATTAIN data is phase 3.
availability speculation must be flaired Speculation
phase 7 data is interesting, phase 24 will tell the real story
ATTAIN and ACHIEVE are phase 10 trials
Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.
- 1small molecule purity is different testing than peptides12 comments in this branch · started by u/joaquin_trevino
- 2oral non-peptide agonist is small molecule, no food restrictions8 comments in this branch · started by u/ice_pack_audit