ATTAIN: the version I wish someone had shown me in week 1
Right, the oral GLP-1 question again, but with numbers this time.
I have 5 data points over 40 weeks. The pattern is consistent enough that I do not think it is chance, and boring enough that nobody is going to screenshot it, which is usually a good sign.
The thing I would flag for anyone new: the effect I am describing showed up at week 44, not week 93. People give up long before the interesting part.
Interested in whether this matches other people's logs or whether I am an outlier.
best — the order this archive was captured in
Respectfully this is a sample of one presented as a finding.
Retitled to remove editorialising. Put the evidence in the body.
the supply conversation changes if this approves
Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.
small molecule, not a peptide, purity discussion is different
No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.
small molecule, not a peptide, purity discussion is different
Not to be pedantic but orforglipron and ATTAIN are being used interchangeably and they are not interchangeable in real life.
oral non-peptide agonist is ACHIEVE, no food restrictions
oral non-peptide agonist is ACHIEVE, no food restrictions
Adding to this: oral GLP-1 is doing more work than the comment implies.
ATTAIN and ACHIEVE are phase 3 trials
Strongly agree. The supply impact would be huge.
Water content matters more than people think. If a vial is carrying residual moisture, your "10mg" is not 10mg of peptide.
Strongly agree. The supply impact would be huge.
Strongly agree. The supply impact would be huge.
Week 87 for me and the honest summary is: 45kg down, the food-noise thing manageable, and I have thought about food maybe four times today.
- 1small molecule, not a peptide, purity discussion is different7 comments in this branch · started by u/taper_off_tabitha
- 2Strongly agree. The supply impact would be huge.6 comments in this branch · started by u/meera_sandvik