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c/orforglipron·submitted 2 years ago by u/purity_pedant

ATTAIN: the version I wish someone had shown me in week 1

Discussionbranch of 6 comments

Right, the oral GLP-1 question again, but with numbers this time. I have 5 data points over 40 weeks. The pattern is consistent enough that I do not think it is chance, and boring enough that nobody is going to screenshot it, which is usually a good sign. The thing I would flag for anyone new: the effect I am…

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6 comments, started 2 years ago
u/meera_sandvik3 points·2 years ago

Strongly agree. The supply impact would be huge.

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u/piotr_bruun-26 points·2 years ago

Water content matters more than people think. If a vial is carrying residual moisture, your "10mg" is not 10mg of peptide.

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[removed]1 point·2 years ago

[removed by moderator]

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u/viktor_laurent1 point·2 years ago

Strongly agree. The supply impact would be huge.

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u/taper_off_tabitha1 point·2 years ago

Strongly agree. The supply impact would be huge.

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u/purity_pedantOPanalytical1 point·2 years ago

Week 87 for me and the honest summary is: 45kg down, the food-noise thing manageable, and I have thought about food maybe four times today.

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The small-molecule oral: why a non-peptide agonist escapes the absorption problems of oral semaglutide, what the ATTAIN and ACHIEVE readouts showed, and what a pill with no refrigeration requirement would do to the entire supply conversation this site is built around.

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