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c/glp1women·posted 6 months ago by u/signe_villalobos

PCOS — my 11-week log, condensed into one table

PCOS Receipts ×2 Cold Box ×3

I have had 7 orders now and I keep a table, so here is the honest summary rather than a vibe.

Material has been consistent. Communication has not. Shipping has varied by about 16 days on nominally the same lane, which matters more in summer than in February.

The independent number came back 99.0% against a claimed 99.1%, which I read as agreement rather than a discrepancy — inter-lab variance on this assay is a point or two either way and treating one lab as ground truth is how people end up in pointless arguments with vendors.

Batch number is in the comments. Ask if you want the method.

1,129 up / 194 down85% upvoted51 commentsid 94446212 Jan 2026

51 comments

24 in this archive, depth 4

best — the order this archive was captured in

u/kian_solberg230 points·6 months ago

Yeah, insulin resistance is under-researched.

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u/signe_villalobosOP165 points·6 months ago

Came off after 24 weeks for financial reasons. Regained about a third over the following year. Back on now at a much lower dose.

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u/kian_solberg53 points·6 months ago

perimenopause and menopause weight physiology

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u/aleksi_eriksen153 points·6 months ago

Week 82 for me and the honest summary is: 28kg down, early fullness manageable, and I have thought about food maybe four times today.

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u/joaquin_wojcik121 points·6 months ago

Water content matters more than people think. If a vial is carrying residual moisture, your "10mg" is not 10mg of peptide.

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[deleted]79 points·6 months ago

[deleted]

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u/katrin_diallo42 points·6 months ago

the trials mostly studied men, perimenopause skipped

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u/sterile_field_steph95 points·6 months ago

Respectfully this is a sample of one presented as a finding.

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u/ferran_mensah33 points·6 months ago

the cycle tracking data matters, keep it private

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u/enzo_fonseca8 points·6 months ago

the cycle tracking data matters, keep it private

Disagree on that part. 98.4% and 98.3% on the same vial is normal.

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u/zaid_roos36 points·6 months ago

Strongly agree. Cycle changes are documented.

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u/honest_syringe58 points·6 months ago

Crossposting this to c/darkspot because the people who need it are not reading this community.

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u/zaid_grimaldi47 points·6 months ago

You have restated the marketing copy. What is the actual substance here.

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u/signe_villalobosOP35 points·6 months ago

the cycle tracking data matters, keep it private

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u/careful_gradient37 points·6 months ago·edited

How many weeks between the two measurements?

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u/signe_villalobosOP0 points·6 months ago

Ireland here. Waited 24 months on a list, gave up, went private, and the total cost was roughly what I expected.

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u/dilara_szabo29 points·6 months ago

contraception interaction claims need citation

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u/vito_beaulieu16 points·6 months ago

Second this question. I have wondered about insulin resistance for 13 months and never seen a straight answer.

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About c/glp1women

The questions the trials under-powered: PCOS and insulin resistance, cycle changes, fertility signal and contraception interactions, perimenopause and menopause weight physiology, and the fact that the pregnancy answer is always "not while trying, talk to your clinician".

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