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c/glp1women·posted 1 months ago by u/hair_shed_hannah

the PCOS question that gets asked weekly, answered properly

Caution Receipts ×3

contraception. That is the whole post, but I will justify it.

Everything else people worry about in c/glp1muscle is downstream of it. Titration speed, reflux, the endless dose arguments — most of it resolves if you sort contraception out first, and almost nobody does.

I say this having got it wrong for 2 months. My ApoB was the thing that eventually made me pay attention, which is a stupid way to learn a lesson that was in the sidebar the whole time.

386 up / 67 down85% upvoted23 commentsid 16ejwt11 Jun 2026

23 comments

15 in this archive, depth 5

best — the order this archive was captured in

u/devils_advocate_d24 points·1 months ago

This is correct. PCOS is real.

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u/column_dead_volume20 points·1 months ago·edited

That is net peptide content, not purity. Different number, different meaning.

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u/hair_shed_hannahOP12 points·1 months ago

The fatigue was genuinely awful for three weeks and then simply stopped. I know that is not useful information, but it is what happened.

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u/hair_shed_hannahOP7 points·1 months ago

You have restated the marketing copy. What is the actual substance here.

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u/yusuf_ramos5 points·1 months ago

Small correction: the trial was 3 weeks, not 35. Does not change your point but people will quote it.

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u/hair_shed_hannah3 points·1 months ago

fertility signal is there but unclear

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[deleted]2 points·1 months ago

[deleted]

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u/reads_the_wiki1 point·1 months ago

Second this question. I have wondered about contraception for 2 months and never seen a straight answer.

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u/hair_shed_hannahOP9 points·1 months ago

That is net peptide content, not purity.

Adding to this: perimenopause is doing more work than the comment implies.

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u/gentle_correctionnice about it-4 points·1 months ago

the cycle question is under-powered in trials

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u/aleksi_eriksen-6 points·1 months ago

Stalled for 17 weeks, changed nothing, and it started moving again on week 56.

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u/kian_solberg1 point·1 months ago

PCOS and insulin resistance

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u/honest_syringe1 point·1 months ago

That is net peptide content, not purity. Different number, different meaning.

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u/sterile_field_steph1 point·1 months ago

the PCOS question is under-powered in trials

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About c/glp1women

The questions the trials under-powered: PCOS and insulin resistance, cycle changes, fertility signal and contraception interactions, perimenopause and menopause weight physiology, and the fact that the pregnancy answer is always "not while trying, talk to your clinician".

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