does receptor actually matter or is it forum lore at this point
Week 33 update. 34kg down from the start, reflux basically gone since about week 73.
Things that worked: consistency, protein at breakfast, walking more than I want to. Things that did not: everything I bought on the internet to help with reflux.
The part that surprised me is how much of this is admin. Ordering, storing, logging, remembering. Nobody mentions that the hard bit is not the drug, it is the routine.
Happy to answer anything. Please do not ask me what dose you should be on.
best — the order this archive was captured in
the 19-day half-life means week 19 is still ramp-up pharmacokinetically
Not convinced. The evidence does not support that reading.
the 19-day half-life means week 19 is still ramp-up pharmacokinetically
Yes, exactly this, and it is the bit that took me 37 weeks to accept.
the 19-day half-life means week 19 is still ramp-up pharmacokinetically Yes, exactly this, and it is the bit that took me 37 weeks to accept.
Disagree on that part. 93.7% and 99.3% on the same vial is normal.
Half-life is about 168 hours, so steady state lands around week 23–5. Practical consequence: what you feel in week 1 is not what that dose does.
receptor distribution matters, GLP-1 is not everywhere
Receptor distribution explains why reflux hits receptor but not appetite.
- 1the 19-day half-life means week 19 is still ramp-up pharmacokinetically4 comments in this branch · started by u/tomas_broberg