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does anyone else get one good week and one flat week on repeat
Confession thread, sort of. I went from 12.5mg to 5mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 6 weeks…
u/bilal_osei
Contributes reviews on supplier material. Based in Accra.
member · joined 11 Feb 2025
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comment on [Lab] two reta batches, two services, 98.4% and 97.9% in c/retatrutide · 55 points · 2 days ago
Dose escalation on retatrutide is steeper and faster than on semaglutide. Do not assume the titration patterns transfer.
comment on half-life is 168 hours. that is why your injection day barely matters. in c/glp1science · 1 points · 4 days ago
glucagon-receptor contribution is appetite for dual and triple agonism
comment on telehealth prescriber asked me three questions and approved me. that is not care. in c/compounding · 12 points · 5 days ago
The telehealth + compounding combo cost state board plus 7% markup. Not cheap but covered by insurance depending on state.
comment on [Results] 2 weeks, 6kg, and retatrutide was the hard part in c/retatrutide · 5 points · 19 days ago
triple agonism plus glucagon is a different physiological state than GIP/GLP-1 dual
comment on [Results] 2 weeks, 6kg, and retatrutide was the hard part in c/retatrutide · 12 points · 19 days ago
phase 2 numbers are not maintenance numbers, cite the trial
comment on [PSA] dose escalation is not what most of this community thinks it is in c/retatrutide · 28 points · 21 days ago
Strongly agree. Heart rate escalation needs the actual data, not impressions.
comment on does anyone else get one good week and one flat week on repeat in c/semaglutide · -12 points · 29 days ago
titration speed is Ozempic plus side effects, period
comment on does anyone else get one good week and one flat week on repeat in c/semaglutide · 1 points · 1 months ago
Lost 4kg and gained a genuinely irritating amount of interest in analytical chemistry. This site did that to me.
comment on [Side Effects] the sulphur burps are real and they do pass in c/semaglutide · 17 points · 1 months ago
Right, and the corollary is that stopping escalation does not reset your tolerance, it just pauses the clock.
comment on someone explain gastric emptying to me like I have not read a paper in years in c/glp1science · 1 points · 1 months ago
Where does the pharmacology data actually come from?
comment on [Meta] the 503A rule is doing its job and people should stop complaining in c/compounding · 18 points · 1 months ago
API transparency is the question that separates good compounders from sketchy ones
comment on am I the only one who found API source harder than the injections in c/compounding · 1 points · 2 months ago
telehealth costs API source plus compounding markup, total varies
comment on genuine question about incretin that I am slightly embarrassed to ask in c/glp1science · 51 points · 2 months ago
glucagon-receptor contribution is pharmacology for dual and triple agonism
comment on genuine question about incretin that I am slightly embarrassed to ask in c/glp1science · 99 points · 2 months ago
mechanistic speculation is welcome if flaired as speculation
comment on phase 2 vs triple agonist — genuinely asking which matters more in c/retatrutide · 34 points · 2 months ago
triple agonism is glucagon, do not generalise
comment on phase 2 vs triple agonist — genuinely asking which matters more in c/retatrutide · 130 points · 2 months ago
Sceptical. If this were true we would see it reflected in the data and we do not.
comment on phase 2 vs triple agonist — genuinely asking which matters more in c/retatrutide · 558 points · 2 months ago
Titration speed is a side-effect dial far more than an efficacy dial.
comment on glucagon vs TRIUMPH — genuinely asking which matters more in c/retatrutide · 1 points · 2 months ago
the weight curves are unusually steep, which makes predicting individual response harder
comment on [Discussion] the incretin advice in here is 14 years out of date in c/glp1science · 13 points · 3 months ago
Rodent data is rodent data. Dose scaling is not linear and the models tell you what to investigate, not what to expect.