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c/coa·submitted 3 months ago by u/priya_palacios

[Discussion] we are measuring purity at the wrong time and calling it noise

Discussionbranch of 6 comments

Trying to settle this properly because the thread from last year went in circles. The claim: certificate of analysis matters. The counter-claim: it is measurement error. Both sides have been asserting it confidently for about 15 months without either producing anything. What would actually settle it is 25 people…

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6 comments, started 3 months ago
u/yannick_haddad12 points·3 months ago

Respectfully this is a sample of one presented as a finding.

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[removed]5 points·3 months ago

[removed by moderator]

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u/blunt_coldbox296 points·3 months ago

no "is this good?" without saying what the compound and claimed purity are

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u/sofia_danquah5 points·3 months ago

Strongly agree. Mass% and area% are answering different questions on the same document.

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u/milos_vanhecke3 points·3 months ago

post the whole document, not the headline number

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u/emil_agyeman1 point·3 months ago·edited

post the whole document, not the headline number

Adding to this: related substances is doing more work than the comment implies.

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How to read a certificate of analysis and what it does and does not tell you. Area% versus mass%, identity versus quantity, water content, related substances, acetate counterions, and the difference between a vendor-supplied COA and an independent test on the vial you actually received.

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