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c/coa·submitted 2 years ago by u/ismael_eriksen

switched from 12.5mg to 0.5mg and the muscle cramps got better, not worse

Questionbranch of 13 comments

Long-ish post, sorry. tl;dr at the bottom. I have been tracking purity against ApoB for 25 weeks because I could not find anyone who had. The correlation is weaker than I expected, which is itself mildly interesting given how confidently people link the two in here. Caveats up front: one person, one lab, one assay,…

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13 comments, started 2 years ago
u/wanjiru_varga58 points·2 years ago

the method line is doing real work, not just window dressing

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u/ismael_eriksenOP35 points·2 years ago

the counterion is part of the mass you paid for

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u/step_therapy_s22 points·2 years ago

no "is this good?" without saying what the compound and claimed purity are

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u/anecdata_annie42 points·2 years ago

Strongly agree. Mass% and area% are answering different questions on the same document.

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u/wanjiru_varga25 points·2 years ago·edited

No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.

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u/anya_correia20 points·2 years ago·edited

the method line is doing real work, not just window dressing

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u/milos_vanhecke16 points·2 years ago

This is the correct framing. The COA structure matters as much as the number.

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u/laila_wojcik6 points·2 years ago·edited

purity and net content are two different numbers, same vial

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u/ismael_eriksenOP-17 points·2 years ago

the method line is doing real work, not just window dressing

Yes, exactly this, and it is the bit that took me 89 weeks to accept.

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u/tidy_vialdrawer_pls1 point·2 years ago

chromatogram or it did not happen

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u/laila_wojcik30 points·2 years ago

No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.

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u/tuva_aalto17 points·2 years ago

area% is not mass%, and here is exactly why it matters

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u/elodie_yilmaz18 points·2 years ago

No.

Yes, exactly this, and it is the bit that took me 84 weeks to accept.

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How to read a certificate of analysis and what it does and does not tell you. Area% versus mass%, identity versus quantity, water content, related substances, acetate counterions, and the difference between a vendor-supplied COA and an independent test on the vial you actually received.

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