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c/coa·submitted 2 months ago by u/yannick_haddad

[Question] the UK — has anyone got a straight answer on COA

Questionbranch of 9 comments

related substances. That is the whole post, but I will justify it. Everything else people worry about in c/sideeffects is downstream of it. Titration speed, muscle cramps, the endless dose arguments — most of it resolves if you sort related substances out first, and almost nobody does. I say this having got it wrong…

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9 comments, started 2 months ago
u/certified_referenceQC26 points·2 months ago

the batch number or it did not happen

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u/fatima_wojcik16 points·2 months ago

Water content on the document? That affects your concentration math.

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u/priya_palacios13 points·2 months ago

PDF metadata is checkable in fifteen seconds

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u/sofia_danquah10 points·2 months ago

chromatogram or it did not happen

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u/ahmed_rasmussen11 points·2 months ago·edited

Water content on the document?

Yes, exactly this, and it is the bit that took me 77 weeks to accept.

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u/amylin_amyamylin5 points·2 months ago

axis labels included, always

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u/ahmed_rasmussen19 points·2 months ago

That is net peptide content, not purity. Different number, different meaning.

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u/aleksi_eriksen7 points·2 months ago

post the whole document, not the headline number

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u/yannick_haddadOP-8 points·2 months ago

Water content was 3.8%, acetate was 6.2%, purity was 99%, but net peptide was only 90% of the label weight. Perfectly honest, just chemistry.

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How to read a certificate of analysis and what it does and does not tell you. Area% versus mass%, identity versus quantity, water content, related substances, acetate counterions, and the difference between a vendor-supplied COA and an independent test on the vial you actually received.

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