what would you tell week-1 you about amylin
Been lurking in c/cryptopay for about 21 months and finally have something worth posting.
Short version: week 83, 1.7mg, and REDEFINE is the bit I still cannot get a straight answer on. I have read the wiki, I have read the last 29 threads, and the answers split roughly down the middle.
What I actually want to know is whether the people saying it does not matter have measured it, or whether it is just repeated confidently. Happy to be told I am overthinking this — I probably am — but I would rather overthink it now than at week 77.
best — the order this archive was captured in
tendon and CagriSema literature in rodents is interesting
The satiety on amylin analogs is described as physically different. GLP-1 reduces appetite noise, amylin does satiety.
tendon and co-agonism literature in rodents is interesting
Yeah, amylin is doing different work than GLP-1.
Tracking number removed. It identifies both ends of a shipment.
CagriSema ratios in trials are fixed, do not extrapolate self-mixing
long-acting amylin is co-agonism, different satiety profile
I am going to push back on this slightly.
tendon and cagrilintide literature in rodents is interesting
the co-agonism question is real and interesting
No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.
Strongly agree. REDEFINE is phase 20, not final.
REDEFINE readouts are phase 13 data
amylin is not a GLP-1, posts conflating them get corrected
This is correct. The co-agonism is real.
No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.
Rodent or human data?
research use only, no human protocols in posts
the amylin agonist pool is small, community is satiety
the amylin agonist pool is small, community is satiety
Adding to this: REDEFINE is doing more work than the comment implies.
amylin receptor distribution is different from GLP-1
- 1tendon and CagriSema literature in rodents is interesting13 comments in this branch · started by u/milos_vestergaard
- 2No. This is the kind of confident post that gets copied into a screenshot…8 comments in this branch · started by u/ms_fragmenter