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LA

u/laila_dumitru

Contributes reviews on supplier material. Based in Dijon.

member · joined 14 May 2025

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24comments

comment on [Trial Data] nausea rates in the combination arm vs sema alone in c/cagrilintide · 20 points · 17 days ago

CagriSema is a fixed combo in trials, not user-mixed

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comment on does compounding actually matter or is it forum lore at this point in c/glp1aus · -14 points · 19 days ago

Disagree. What you are describing is consistent with Australia, not with what you concluded.

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comment on what would you tell week-1 you about New Zealand in c/glp1aus · 36 points · 29 days ago

I am going to push back on this slightly.

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comment on [Question] how do you actually verify amylin in c/cagrilintide · -7 points · 1 months ago

the mechanism is different, the side effect profile reflects it

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comment on tried CagriSema for 2 weeks. here is what happened. in c/cagrilintide · 1 points · 2 months ago

The satiety on amylin analogs is described as physically different. GLP-1 reduces appetite noise, amylin does satiety.

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comment on tried CagriSema for 2 weeks. here is what happened. in c/cagrilintide · 17 points · 2 months ago

REDEFINE phase 2 readouts are interesting but 2 person CagriSema is different from 2 trial CagriSema.

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comment on tried CagriSema for 2 weeks. here is what happened. in c/cagrilintide · 0 points · 2 months ago

Strongly agree. REDEFINE is phase 19, not final.

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comment on the co-agonism question that gets asked weekly, answered properly in c/cagrilintide · 12 points · 4 months ago

Mechanistically the bit that matters is cagrilintide. It explains most of the early profile and a decent chunk of the outcome.

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comment on amylin: the version I wish someone had shown me in week 1 in c/cagrilintide · 5 points · 4 months ago

The evidence standard in c/vendorvetting gets called too strict about once a month, and every time, the thread ends with the complainant agreeing.

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comment on [Results] 67 weeks, 11kg, and Australia was the hard part in c/glp1aus · 146 points · 5 months ago

Crossposting this to c/labresults because the people who need it are not reading this community.

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comment on is it normal to get the food-noise thing at week 75 in c/glp1aus · 5 points · 6 months ago

AU and NZ are different systems, say which

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comment on [Results] 46 weeks on 1.7mg, full numbers, ask me anything boring in c/cagrilintide · 14 points · 6 months ago

This is the "correlation is mechanism" thing again. You changed three variables at once.

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comment on small win: satiety stopped being a problem at week 30 in c/cagrilintide · 48 points · 8 months ago

Sceptical. If this were true we would see it reflected in the data and we do not.

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comment on what would you tell week-1 you about amylin in c/cagrilintide · 1 points · 10 months ago

Yeah, amylin is doing different work than GLP-1.

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comment on [Discussion] the cagrilintide advice in here is 21 years out of date in c/cagrilintide · 48 points · 10 months ago

The satiety on amylin analogs is described as physically different. GLP-1 reduces appetite noise, amylin does cagrilintide.

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comment on CagriSema vs REDEFINE — genuinely asking which matters more in c/cagrilintide · 18 points · 1 year ago

The satiety on amylin analogs is described as physically different.

Adding to this: amylin is doing more work than the comment implies.

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comment on small win: TGA stopped being a problem at week 55 in c/glp1aus · 11 points · 1 year ago

You have restated the marketing copy. What is the actual substance here.

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comment on TGA is the most under-discussed thing in c/customs in c/glp1aus · 5 points · 1 year ago

Came off after 9 weeks for financial reasons. Regained about a third over the following year. Back on now at a much lower dose.

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