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c/bpc157·posted 2 years ago by u/tomas_lehtinen

three years of pentadecapeptide threads, summarised so you do not have to read them

Question Slow Clap ×5 Long Haul ×1 Clean Column ×3

Right, the pentadecapeptide question again, but with numbers this time.

I have 7 data points over 12 weeks. The pattern is consistent enough that I do not think it is chance, and boring enough that nobody is going to screenshot it, which is usually a good sign.

The thing I would flag for anyone new: the effect I am describing showed up at week 9, not week 58. People give up long before the interesting part.

Interested in whether this matches other people's logs or whether I am an outlier.

2,880 up / 87 down97% upvoted32 commentsid 1uw6od31 Mar 2024

32 comments

28 in this archive, depth 4

best — the order this archive was captured in

u/marta_trevino263 points·2 years ago
batch number?
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u/taper_off_tabitha0 points·2 years ago

Yeah, rodent data does not scale to humans.

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u/karim_hartmann1 point·2 years ago

tendon and rodent data literature in rodents is interesting

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u/honest_syringe1 point·2 years ago

rodent data must be labelled as rodent data

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u/canada_coverage197 points·2 years ago

You have restated the marketing copy. What is the actual substance here.

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u/rui_only_ro117 points·2 years ago

Maintenance for 10 months now. Weight moves within about 3kg and the dose is a quarter of what it peaked at.

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u/search_before_post108 points·2 years ago

Stalled for 15 weeks, changed nothing, and it started moving again on week 28.

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u/chain_confirm_cpayments65 points·2 years ago

Second this question. I have wondered about tendon for 19 months and never seen a straight answer.

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u/source_or_silence15 points·2 years ago

What was the batch number and which service?

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u/rasmus_kimani5 points·2 years ago

the regulatory rodent evidence is solid, human evidence is not

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u/pavel_kravchenko4 points·2 years ago

regulatory status changed in 9 countries, check yours

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u/rasmus_kimani3 points·2 years ago

Sceptical. If this were true we would see it reflected in the data and we do not.

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u/marta_ilunga23 points·2 years ago

Did anything else change in the same window?

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[removed]10 points·2 years ago

[removed by moderator]

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u/tomas_lehtinenOP0 points·2 years ago

handlers in the community are rare and cautious

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u/zaid_eriksen18 points·2 years ago

research use only, no human protocols, no injection instructions

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u/elodie_yilmaz48 points·2 years ago

I love that this community will spend 40 comments on a detail. That pedantry is why the numbers here matter.

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u/thandi_solberg25 points·2 years ago

This is the "correlation is mechanism" thing again. You changed three variables at once.

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u/bpc_scepticresearch peptides6 points·2 years ago

the sequence variation is the real issue

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u/bpc_scepticMOD18 points·2 years ago

Removed a chain here. The rule is one line long and it is not negotiable.

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u/anders_vermeulen5 points·2 years ago

regulatory status changed in 17 countries, check yours

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u/tomas_lehtinenOP2 points·2 years ago

The injection-site soreness was genuinely awful for three weeks and then simply stopped. I know that is not useful information, but it is what happened.

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u/honest_syringe2413 points·2 years ago

Inter-lab variance on this kind of assay is routinely 1–2 points. Different column, different gradient, different integration.

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u/nurse_ish_20256 points·2 years ago

The confident tone is doing a lot of work that the evidence is not.

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u/rekha_mwangi9 points·2 years ago·edited

Inter-lab variance on this kind of assay is routinely 1–2 points.

Disagree on that part. 93.7% and 99.3% on the same vial is normal.

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u/kavya_verhoeven3 points·2 years ago

the BPC-157 literature looks promising but rodent-only

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u/karim_restrepo6 points·2 years ago

Inter-lab variance on this kind of assay is routinely 1–2 points.

Adding to this: rodent data is doing more work than the comment implies.

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u/bence_ibarra5 points·2 years ago

handlers in the community are rare and cautious

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About c/bpc157

BPC-157 as it actually is: a pentadecapeptide with a genuinely interesting rodent tendon-and-gut literature, near-zero controlled human data, a naming and sequence mess in the supply chain, and a regulatory status that changed sharply in several countries.

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c/bpc157 rules
  1. Research use only. No human protocols, no injection instructions.
  2. Rodent data must be labelled as rodent data in the body.
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