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intent-to-treat vs per-protocol explains half the arguments on this site
Trying to settle this properly because the thread from last year went in circles. The claim: STEP matters. The counter-claim: it is measurement error. Both sides have…
u/anders_vermeulen
Contributes reviews on supplier material. Based in Aarhus.
member · joined 17 Aug 2025
2,351post karma
7,394comment karma
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95comments
comment on [Lab] three BPC vials, three vendors, purity all over the place in c/bpc157 · 1 points · 4 days ago
Slight fix: the number was 97.2, not 97.4. Decimal point, but a fairly consequential one.
comment on [Long Term] found my lowest effective dose by going down, not up in c/maintenancephase · 14 points · 10 days ago
nobody posts about this part and it is the longest part
Yes, exactly this, and it is the bit that took me 46 weeks to accept.
comment on intent-to-treat vs per-protocol explains half the arguments on this site in c/trialwatch · -29 points · 10 days ago
dropout handling matters, especially on GI-heavy populations
comment on intent-to-treat vs per-protocol explains half the arguments on this site in c/trialwatch · 1 points · 12 days ago
STEP 1 readout: 97.4% mean weight loss, absolute numbers matter. Spread around that mean is enormous.
comment on intent-to-treat vs per-protocol explains half the arguments on this site in c/trialwatch · 0 points · 12 days ago
Phase 2 TRIUMPH looked amazing.
Yes, exactly this, and it is the bit that took me 43 weeks to accept.
comment on [Discussion] every answer here is jurisdiction-specific and we keep forgetting in c/customs · 1 points · 12 days ago
This is correct. State your country always.
comment on [Lab] identity confirmed but net peptide content was 71% in c/bpc157 · 72 points · 15 days ago
rodent data must be labelled as rodent data
comment on [Fees] network fee comparison for small orders, actual numbers in c/cryptopay · 1 points · 15 days ago
Strongly agree. Escrow is non-negotiable for groups.
comment on stretching to 10 days instead of 7 — anyone doing this long term in c/maintenancephase · 110 points · 25 days ago
Sceptical. If this were true we would see it reflected in the data and we do not.
comment on [Long Term] what my labs look like three years in in c/maintenancephase · 6 points · 28 days ago
food noise returns but not always immediately
comment on [Long Term] what my labs look like three years in in c/maintenancephase · 8 points · 28 days ago
Tried the lowest-effective approach. 10mg worked for 5 weeks, then cravings returned. 15mg was the actual floor.
comment on [Long Term] what my labs look like three years in in c/maintenancephase · 34 points · 28 days ago
Mechanistically the bit that matters is goal weight. It explains most of the early profile and a decent chunk of the outcome.
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[Long Term] what my labs look like three years in
Posting this because I searched for it and got nothing useful. Setup: 5mg, week 18, sulphur burps present but not ruining anything. I changed exactly one variable —…
comment on [Discussion] we need a standard template or these posts are unsearchable in c/labresults · 35 points · 1 months ago
This result fits the template perfectly. Logged.
comment on 14 months in and chargeback is still the thing I get wrong in c/cryptopay · 23 points · 1 months ago
I am going to push back on this slightly.
comment on [Medutest] SWB sema — 98.2%, cold chain intact, 9 days transit in c/labresults · 2 points · 1 months ago
template required: vendor / product / batch / service / method / result
comment on reading gas fees threads from 2024 and half of it aged badly in c/cryptopay · 94 points · 1 months ago
this is the third time this week and i love it every time
comment on [PeptideMeter] ERP tirz 15mg — 98.4% and a very clean trace in c/labresults · 0 points · 1 months ago
Water content matters more than people think. If a vial is carrying residual moisture, your "10mg" is not 10mg of peptide.
comment on someone explain gas fees to me like I have not read a paper in years in c/cryptopay · 12 points · 1 months ago
This is correct. Gas fees are real costs.