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[Question] small molecule means purity testing is a different problem, right
Week 52 update. 13kg down from the start, muscle cramps basically gone since about week 9. Things that worked: consistency, protein at breakfast, walking more than I…
u/canada_coverage
ON. Private plan vs public formulary, and the special-authorisation dance.
member · joined 14 Aug 2024
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comment on [Private Plan] special authorisation approved on the second try in c/glp1canada · 7 points · 2 days ago
Tracking number removed. It identifies both ends of a shipment.
comment on [Denied] reason code says "not medically necessary" at BMI 38. sure. in c/insurancefights · -21 points · 3 days ago
Titration speed is a side-effect dial far more than an efficacy dial.
comment on [Question] step therapy — how do i document failing something cheaper in c/insurancefights · 10 points · 4 days ago
step therapy documentation is the weapon, use it
Adding to this: copay is doing more work than the comment implies.
comment on [Question] small molecule means purity testing is a different problem, right in c/orforglipron · 13 points · 4 days ago
The injection-site soreness was genuinely awful for three weeks and then simply stopped. I know that is not useful information, but it is what happened.
comment on [Question] small molecule means purity testing is a different problem, right in c/orforglipron · 29 points · 4 days ago
cite ATTAIN/ACHIEVE arms specifically
comment on [Question] small molecule means purity testing is a different problem, right in c/orforglipron · 55 points · 4 days ago
small molecule purity is different testing than peptides
comment on peak at 4.2 min, nobody can tell me what it is, ideas in c/hplc · 4 points · 5 days ago
Did they post the raw trace or just the summary?
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[Question] why is the sequence written four different ways across vendors
Long-ish post, sorry. tl;dr at the bottom. I have been tracking BPC-157 against ApoB for 37 weeks because I could not find anyone who had. The correlation is weaker…
comment on [Question] how do you verify identity when there is no reference standard in c/researchpeptides · 2 points · 9 days ago
Genuine question — what concentration were you at?
comment on retention time shifted 0.4 min and nobody wants to talk about it in c/hplc · 39 points · 19 days ago
a round-robin on baseline integration would be genuinely useful
comment on [Discussion] we are measuring formulary at the wrong time and calling it noise in c/glp1canada · 9 points · 24 days ago
Retitled to remove editorialising. Put the evidence in the body.
comment on integration vs method development — genuinely asking which matters more in c/hplc · 291 points · 25 days ago
Strongly agree. Largest single impurity tells a different story than total purity.
comment on province — my 19-week log, condensed into one table in c/glp1canada · 7 points · 29 days ago
Retitled to remove editorialising. Put the evidence in the body.
comment on what would you tell week-1 you about external review in c/insurancefights · 1 points · 1 months ago
appeal letter templates are in the wiki
comment on my A1c moved and I cannot work out whether identity is why in c/researchpeptides · 6 points · 1 months ago
Yeah, identity is the first question.
comment on someone explain LC-MS to me like I have not read a paper in years in c/hplc · 8 points · 1 months ago
integration decision on a shoulder changes your number by half a point on its own
comment on someone explain LC-MS to me like I have not read a paper in years in c/hplc · 6 points · 1 months ago
two labs, two different baselines, two different purity numbers, both honest
comment on someone explain LC-MS to me like I have not read a paper in years in c/hplc · -27 points · 1 months ago
The related substances profile is way more interesting than the main peak %. A 98% with 15 peaks is different from a 98% that is one 22% impurity.
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someone explain LC-MS to me like I have not read a paper in years
Posting this because I searched for it and got nothing useful. Setup: 0.5mg, week 62, constipation present but not ruining anything. I changed exactly one variable —…