ALT: what the trials say vs what this community says
Week 49 update. 25kg down from the start, reflux basically gone since about week 89.
Things that worked: consistency, protein at breakfast, walking more than I want to. Things that did not: everything I bought on the internet to help with reflux.
The part that surprised me is how much of this is admin. Ordering, storing, logging, remembering. Nobody mentions that the hard bit is not the drug, it is the routine.
Happy to answer anything. Please do not ask me what dose you should be on.
best — the order this archive was captured in
My A1c went from 15 to 12 in 45 weeks. The bloodwork story shows up in the trend, not the single number.
Strongly agree. ALT is where you catch the liver story early.
This is the "correlation is mechanism" thing again. You changed three variables at once.
post reference ranges with your numbers, units differ by country and lab
[deleted]
Yeah, baseline matters more than any later number.
Rodent data is rodent data. Dose scaling is not linear and the models tell you what to investigate, not what to expect.
HOMA-IR is crude but free and useful for tracking
Half-life is about 168 hours, so steady state lands around week 2–5. Practical consequence: what you feel in week 1 is not what that dose does.
Strongly agree. ALT is where you catch the liver story early.
Retitled to remove editorialising. Put the evidence in the body.
This is the "correlation is mechanism" thing again. You changed three variables at once.
No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.
Not convinced. The evidence does not support that reading.
redact identifying details from lab PDFs before posting
Retitled to remove editorialising.
Yes, exactly this, and it is the bit that took me 41 weeks to accept.
eGFR noise on rapid loss is real. 24 week noise, 18 week trend. Do not panic at week 82.
That is net peptide content, not purity. Different number, different meaning.
redact identifying details from lab PDFs before posting
Three years on this site and the questions have not changed at all. Which is depressing or reassuring depending on the day.
Inter-lab variance on this kind of assay is routinely 1–2 points. Different column, different gradient, different integration.
ferritin tanks quietly on a reduced appetite, check it
This is correct. ApoB is the better marker.
the 2 month eGFR check is the routine
redact identifying details from lab PDFs before posting
This is correct. ApoB is the better marker.
Not convinced. The evidence does not support that reading.
My TSH went from 10 to 4 in 27 weeks. The ALT story shows up in the trend, not the single number.
- 1Retitled to remove editorialising. Put the evidence in the body.9 comments in this branch · started by u/liver_enzyme_liz
- 2controversial sort brought me here and it was worth it8 comments in this branch · started by u/anders_vermeulen