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[Discussion] we underplay how much of the GI stuff is dose-escalation speed
Posting this because I searched for it and got nothing useful. Setup: 7.5mg, week 47, sulphur burps present but not ruining anything. I changed exactly one variable —…
u/liv_okafor
Contributes reviews on supplier material. Based in Oulu.
member · joined 11 Feb 2025
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comment on [PSA] severe abdominal pain is not a forum question in c/sideeffects · 38 points · 4 days ago
resting heart rate moved up 20 bpm and settled back down when I stopped escalating
comment on [Explainer] integration decisions change your number more than the sample does in c/hplc · 31 points · 8 days ago
Not to be pedantic but chromatogram and HPLC are being used interchangeably and they are not interchangeable in real life.
comment on [Question] my TSH moved 0.4. is that anything. in c/bloodwork · 12 points · 12 days ago
Baseline TSH: 98.3. Week 89: 96.8. Same lab, fasted, same time of day. Trend matters.
comment on [Update] week 30, appetite returning, dose unchanged, weight flat in c/dosinglogs · 8 points · 23 days ago
Yeah, the consistency is the value.
comment on [Discussion] we underplay how much of the GI stuff is dose-escalation speed in c/sideeffects · 1 points · 24 days ago
The muscle cramps was genuinely awful for three weeks and then simply stopped. Week 39 me did not think I would make it to week 2.
comment on someone explain chromatogram to me like I have not read a paper in years in c/hplc · -16 points · 1 months ago
Yeah, the chromatogram profile matters more than the headline number.
comment on anyone else notice gallbladder kicking in around week 39 in c/sideeffects · 11 points · 1 months ago
Sceptical. If this were true we would see it reflected in the data and we do not.
comment on my eGFR moved and I cannot work out whether LC-MS is why in c/hplc · 85 points · 1 months ago
Not convinced. The evidence does not support that reading.
comment on help me understand A1c, I have read the wiki twice in c/bloodwork · 14 points · 1 months ago
ALT is where the fatty-liver story shows up first
comment on [Meta] the hair loss rule is doing its job and people should stop complaining in c/sideeffects · 170 points · 1 months ago
The reflux was genuinely awful for three weeks and then simply stopped. Week 74 me did not think I would make it to week 28.
comment on what would you tell week-1 you about fatigue in c/sideeffects · 21 points · 2 months ago
Same experience. Week 64 and it simply stopped. I know that is not useful information but it is what happened.
comment on why does nobody talk about chromatogram in c/hplc · 15 points · 2 months ago
Disagree but this is the good kind of wrong — it is specific enough to be checked.
comment on [Vendor] QST order #13 — Denmark, 39 days, no drama, receipts inside in c/sideeffects · 9 points · 2 months ago
hair loss is real and usually reversible when you stabilize
comment on unpopular opinion: method development is massively overrated in c/hplc · 5 points · 2 months ago
two labs, two different baselines, two different purity numbers, both honest
comment on three years of weight threads, summarised so you do not have to read them in c/dosinglogs · 32 points · 2 months ago
long-running logs are the value
comment on sulphur burps is the most under-discussed thing in c/orforglipron in c/sideeffects · 10 points · 2 months ago
nausea on day 2 is normal, nausea after week 9 is worth checking
comment on three years of ALT threads, summarised so you do not have to read them in c/bloodwork · 46 points · 3 months ago
No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.
comment on am I the only one who found fatigue harder than the injections in c/sideeffects · 18 points · 3 months ago
IANAD and neither is anyone upvoting this
comment on what would you tell week-1 you about LC-MS in c/hplc · 64 points · 3 months ago
area% and mass% are not the same and this whole post conflates them