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c/bloodwork·posted 2 years ago by u/diego_sorensen

lipids is the most under-discussed thing in c/dosinglogs

Concerning Well Actually ×9 Clean Column ×1 Cold Box ×1

Something I noticed reading old threads that I have not seen said out loud.

The advice on ApoB in this community changed substantially around the start of last year, and nobody went back and updated the older posts. So depending on which thread the search engine hands you, you get two contradictory answers with the same confidence.

I have listed what I think the current consensus is below. Correct me — that is the point of posting it.

6,834 up / 811 down89% upvoted35 commentsid 2d04sp21 Nov 2023

35 comments

30 in this archive, depth 5

best — the order this archive was captured in

u/a1c_arcMOD1.1k points·2 years ago

Flair changed to match the content. Read the sidebar before posting next time and we are square.

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u/chidi_abubakar808 points·2 years ago

baseline is the most important ferritin measurement, you cannot collect it later

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u/signe_grimaldi344 points·2 years ago

eGFR noise during rapid loss is expected

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u/neha_rahimi-13 points·2 years ago
search before post, but also, welcome
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u/jarno_karlsen568 points·2 years ago

This is the "correlation is mechanism" thing again. You changed three variables at once.

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u/customs_seizure_sid378 points·2 years ago

triglycerides from 18 to 6 is movement, not noise

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u/chidi_abubakar183 points·2 years ago

Disagree but this is the good kind of wrong — it is specific enough to be checked.

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u/vito_chowdhury406 points·2 years ago·edited
i have this exact spreadsheet
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[removed]279 points·2 years ago

[removed by moderator]

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u/diego_sorensenOP200 points·2 years ago

A1c moves slowly, quarterly is plenty

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u/diego_sorensenOP156 points·2 years ago

post reference ranges with your numbers, units differ by country and lab

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u/edit_for_clarity122 points·2 years ago·edited

post reference ranges with your numbers, units differ by country and lab

Adding to this: ferritin is doing more work than the comment implies.

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u/hedda_adeyemi29 points·2 years ago

post reference ranges with your numbers, units differ by country and lab

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u/coldchain_karencold chain18 points·2 years ago

Yeah, baseline matters more than any later number.

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u/rekha_mwangi172 points·2 years ago

ferritin tanks quietly on a reduced appetite, check it

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u/anders_vermeulen72 points·2 years ago

ferritin tanks quietly on a reduced appetite, check it

Adding to this: ApoB is doing more work than the comment implies.

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u/cold_chromatogram3146 points·2 years ago

ApoB over LDL-C, that is the hierarchy

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u/emil_agyeman221 points·2 years ago

This is correct. ApoB is the better marker.

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u/heart_rate_bump0 points·2 years ago

This is the "correlation is mechanism" thing again. You changed three variables at once.

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u/coa_forgery_watch325 points·2 years ago

triglycerides from 12 to 18 is movement, not noise

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u/emeka_chowdhury184 points·2 years ago

Mechanistically the bit that matters is ALT. It explains most of the early profile and a decent chunk of the outcome.

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u/diego_sorensenOP145 points·2 years ago

My ApoB went from 3 to 21 in 9 weeks. The eGFR story shows up in the trend, not the single number.

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u/skip_week_sceptic70 points·2 years ago

the 22 month bloodwork check is the routine

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u/britt_marchand43 points·2 years ago

the 20 month lipids check is the routine

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u/cormac_erdogan140 points·2 years ago

ALT is where the fatty-liver story shows up first

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u/no_refunds_nr87 points·2 years ago

Strongly agree. ALT is where you catch the liver story early.

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u/ahmed_fonseca33 points·2 years ago

Small correction: the trial was 3 weeks, not 36. Does not change your point but people will quote it.

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u/step_therapy_s76 points·2 years ago

Titration speed is a side-effect dial far more than an efficacy dial.

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u/constipation_clubside effects54 points·2 years ago

ApoB over LDL-C, that is the hierarchy

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About c/bloodwork

What to measure before you start, what to re-measure, and how to interpret movement without panicking. ApoB over LDL-C, HOMA-IR as a crude free tool, ALT and the fatty-liver story, eGFR noise during rapid loss, and the deficiencies that a 1,100-calorie appetite will hand you.

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