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c/bloodwork·posted 1 year ago by u/yara_antonsen

the ALT thing finally clicked for me and I want to write it down

Question The Quiet One ×6

Been lurking in c/intlshipping for about 10 months and finally have something worth posting.

Short version: week 34, 1.7mg, and ALT is the bit I still cannot get a straight answer on. I have read the wiki, I have read the last 37 threads, and the answers split roughly down the middle.

What I actually want to know is whether the people saying it does not matter have measured it, or whether it is just repeated confidently. Happy to be told I am overthinking this — I probably am — but I would rather overthink it now than at week 28.

1,125 up / 376 down75% upvoted47 commentsid 142i4x7 Jan 2025

47 comments

25 in this archive, depth 5

best — the order this archive was captured in

u/santiago_rasmussen128 points·1 year ago

nobody here can tell you what a result means for you

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u/amara_dziedzic43 points·1 year ago

nobody here can tell you what a result means for you

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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u/yara_antonsenOP-38 points·1 year ago

eGFR noise on rapid loss is real. 3 week noise, 22 week trend. Do not panic at week 58.

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u/yara_antonsenOP0 points·1 year ago

Respectfully this is a sample of one presented as a finding.

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u/elin_varga0 points·1 year ago

baseline is the most important baseline labs measurement, you cannot collect it later

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u/gentle_correctionMOD61 points·1 year ago

This is an urgent-care question wearing a forum question's clothes. Please contact a clinician rather than waiting for replies.

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[deleted]23 points·1 year ago

[deleted]

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u/thermal_mass_tom25 points·1 year ago

A1c moves slowly, quarterly is plenty

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u/vito_chowdhury15 points·1 year ago·edited

Strongly agree. ALT is where you catch the liver story early.

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u/ahmed_fonseca43 points·1 year ago

Inter-lab variance on this kind of assay is routinely 1–2 points. Different column, different gradient, different integration.

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u/elin_varga62 points·1 year ago

Water content matters more than people think. If a vial is carrying residual moisture, your "10mg" is not 10mg of peptide.

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u/thyroid_tangent15 points·1 year ago

ALT is where the fatty-liver story shows up first

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u/yara_mensah8 points·1 year ago

Yeah, baseline matters more than any later number.

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u/anya_rautio32 points·1 year ago

Three years on this site and the questions have not changed at all. Which is depressing or reassuring depending on the day.

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u/skip_week_sceptic18 points·1 year ago

This is correct. ApoB is the better marker.

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u/cormac_roos19 points·1 year ago

Strongly agree. ALT is where you catch the liver story early.

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u/anders_vermeulen9 points·1 year ago

My ALT went from 18 to 6 in 70 weeks. The lipids story shows up in the trend, not the single number.

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u/santiago_rasmussen5 points·1 year ago

My ALT went from 18 to 6 in 70 weeks.

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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u/diego_sorensen10 points·1 year ago

redact identifying details from lab PDFs before posting

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u/mikkel_ogunleye12 points·1 year ago

Crossposting this to c/meta because the people who need it are not reading this community.

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About c/bloodwork

What to measure before you start, what to re-measure, and how to interpret movement without panicking. ApoB over LDL-C, HOMA-IR as a crude free tool, ALT and the fatty-liver story, eGFR noise during rapid loss, and the deficiencies that a 1,100-calorie appetite will hand you.

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