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u/gastric_emptying_g

Delayed gastric emptying explains most of the GI story and half the satiety story.

member · joined 27 Sep 2024

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117comments

Comments — page 5 of 5

comment on 22 months in and timeframe is still the thing I get wrong in c/progresspics · 58 points · 1 year ago

Week 74 for me and the honest summary is: 40kg down, muscle cramps manageable, and I have thought about food maybe four times today.

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comment on 22 months in and timeframe is still the thing I get wrong in c/progresspics · 0 points · 1 year ago

Yeah, text-only removes the comparison.

Yes, exactly this, and it is the bit that took me 96 weeks to accept.

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comment on week 56 check-in — 17kg down, muscle cramps manageable, one thing confusing me in c/glp1eu · 332 points · 1 year ago

Strongly agree. Pricing is local.

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comment on three years of SELECT threads, summarised so you do not have to read them in c/trialwatch · 1 points · 1 year ago

That is net peptide content, not purity. Different number, different meaning.

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comment on what would you tell week-1 you about area percent in c/coa · 49 points · 1 year ago

PDF metadata is checkable in fifteen seconds

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comment on [Question] water content — what am I missing here in c/coa · 157 points · 1 year ago

Yeah, 96.8% area is not the problem, the missing impurity breakdown is the problem.

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comment on [Discussion] the endpoint advice in here is 5 years out of date in c/trialwatch · 48 points · 1 year ago

No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.

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comment on [Discussion] the endpoint advice in here is 5 years out of date in c/trialwatch · 14 points · 1 year ago

SURMOUNT-4 discontinuation arm showed regain. That is the reality of a chronic disease treatment, not a failure.

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comment on [Lab] SSA BPC — Medutest came back 97.4% against a claimed 98.3% in c/glp1science · 3 points · 1 year ago

cite the paper: journal, year, first author, links optional

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comment on my TSH moved and I cannot work out whether receptor is why in c/glp1science · 1 points · 1 year ago

do not extrapolate rodent data to human dosing without saying so

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comment on my TSH moved and I cannot work out whether receptor is why in c/glp1science · 3 points · 1 year ago

The half-life is 14 hours, which means week 14 is genuinely still ramp-up. Week 31 is steady state.

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comment on my TSH moved and I cannot work out whether receptor is why in c/glp1science · 0 points · 1 year ago

The half-life is 7 hours, which means week 7 is genuinely still ramp-up. Week 16 is steady state.

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comment on someone explain goal to me like I have not read a paper in years in c/progresspics · 1 points · 1 year ago

No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.

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comment on [Discussion] can we stop arguing about endpoint until somebody posts a number in c/trialwatch · 101 points · 1 year ago

Half-life is about 168 hours, so steady state lands around week 18–5. Practical consequence: what you feel in week 1 is not what that dose does.

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comment on stalled for 9 weeks at 10mg and I refuse to panic this time in c/coa · 1 points · 1 year ago

Strongly agree. Mass% and area% are answering different questions on the same document.

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comment on is it normal to get early fullness at week 19 in c/scamalerts · 6 points · 1 year ago

PDF metadata said the COA was created in a browser four months after the date printed on the page. Worth flagging.

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comment on Spain: batch, and what it actually costs here in c/coa · 30 points · 1 year ago

Metadata check caught a COA that was created in a browser four months after the analysis date. Not evidence of fraud, but worth flagging to KP.

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comment on [Results] 32 weeks, 31kg, and pharmacology was the hard part in c/glp1science · 60 points · 1 year ago

Flair changed to match the content. Read the sidebar before posting next time and we are square.

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comment on [Discussion] the receptor advice in here is 4 years out of date in c/glp1science · 140 points · 1 year ago

incretin physiology is half-life, the mechanism layer

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comment on related substances — my 21-week log, condensed into one table in c/coa · 474 points · 1 year ago

no "is this good?" without saying what the compound and claimed purity are

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