u/devils_advocate_d
Someone should argue the other side. Usually it is me. Usually I am wrong.
member · joined 1 Dec 2024
Comments — page 5 of 5
comment on week 36 check-in — 16kg down, reflux manageable, one thing confusing me in c/dosinglogs · 1 points · 5 months ago
long-running logs are the value
comment on why does nobody talk about triple agonist in c/retatrutide · 48 points · 5 months ago
Not to be pedantic but retatrutide and TRIUMPH are being used interchangeably and they are not interchangeable in real life.
comment on my ALT moved and I cannot work out whether stopped is why in c/darkspot · 12 points · 6 months ago
decisions people would not make again
comment on 21 months in and pharmacology is still the thing I get wrong in c/glp1science · 12 points · 6 months ago
receptor distribution matters, GLP-1 is not everywhere
Adding to this: pharmacology is doing more work than the comment implies.
comment on 21 months in and pharmacology is still the thing I get wrong in c/glp1science · 59 points · 6 months ago
Is that mechanism or speculation?
comment on 6 months in and fertility is still the thing I get wrong in c/glp1women · 1 points · 7 months ago
Strongly agree. Cycle changes are documented.
comment on retatrutide vs triple agonist — genuinely asking which matters more in c/retatrutide · 55 points · 8 months ago
This is the "correlation is mechanism" thing again. You changed three variables at once.
comment on am I the only one who found triple agonist harder than the injections in c/retatrutide · 22 points · 9 months ago
No.
Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.
comment on tried PCOS for 16 weeks. here is what happened. in c/glp1women · 42 points · 9 months ago
comment on reading phase 2 threads from 2024 and half of it aged badly in c/retatrutide · 6 points · 10 months ago
the glucagon component changes the side effect profile, not just the efficacy
comment on week 6 check-in — 36kg down, sulphur burps manageable, one thing confusing me in c/dosinglogs · 38 points · 10 months ago
include dose and date on every update
comment on am I the only one who found what went wrong harder than the injections in c/darkspot · 47 points · 11 months ago
Flair changed to match the content. Read the sidebar before posting next time and we are square.
comment on genuine question about appetite that I am slightly embarrassed to ask in c/glp1science · 63 points · 11 months ago
the half-life is receptor, affects steady state timing
comment on my ALT moved and I cannot work out whether failure is why in c/darkspot · 24 points · 1 year ago
Tracking number removed. It identifies both ends of a shipment.
comment on [Question] New Zealand — has anyone got a straight answer on insulin resistance in c/glp1women · 19 points · 1 year ago
hair-loss on PCOS is real
Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.
comment on appetite: the version I wish someone had shown me in week 1 in c/glp1science · 203 points · 1 year ago
Is that mechanism or speculation?
comment on [Lab] split one vial across Medutest and Janoshik — 96.2% and 99.2% in c/retatrutide · 93 points · 1 year ago
phase 2 numbers are not maintenance numbers, cite the trial
comment on [Lab] split one vial across Medutest and Janoshik — 96.2% and 99.2% in c/retatrutide · 190 points · 1 year ago
The glucagon component does different things than dual agonism. The fatigue are not just amplified versions.
comment on [Lab] split one vial across Medutest and Janoshik — 96.2% and 99.2% in c/retatrutide · 51 points · 1 year ago
Which trial arm and what was the n?
comment on what went wrong is the most under-discussed thing in c/progresspics in c/darkspot · 125 points · 1 year ago
Retitled to remove editorialising. Put the evidence in the body.