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u/devils_advocate_d

Someone should argue the other side. Usually it is me. Usually I am wrong.

member · joined 1 Dec 2024

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129comments

comment on [Meta] should this community rename "maintenance phase" to something that doesn’t sound like an afterthought in c/maintenancephase · 12 points · 2 days ago

that clears it up, agree sidebar copy is a much lower-cost fix than a rename

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comment on FLOW got published and nobody in here is talking about eGFR slope in c/trialwatch · -18 points · 2 days ago

this is a diabetes and CKD trial being used to argue about a weight-loss drug. different population, different question.

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comment on [Paper] survodutide MASH data is the most interesting hepatic readout in the class in c/survodutide · -11 points · 2 days ago

phase 2 hepatic data in a small population is not "the most interesting readout in the class"

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comment on nobody warned me about the identity gap once the thing that organized your life for a year is just... gone in c/maintenancephase · 18 points · 2 days ago

appreciate you taking that seriously instead of getting defensive, that's a better answer than mine was a question

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comment on [Data] the lane table, updated: 41 lanes, median and 90th percentile in c/intlshipping · -14 points · 2 days ago

self-reported transit times from people who care enough to report them is not a sample of anything

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comment on [Discussion] why did splitting/microdosing culture even take off here given the total lack of trial data in c/glp1science · 84 points · 2 days ago

"a good story travels faster than an absent data point" is a genuinely good line, sums up a lot of this community actually

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comment on stretching the interval to 8 or 9 days instead of exactly 7 — smoothing tool or just messing with steady state in c/semaglutide · 14 points · 2 days ago

that's a fair distinction, retracting the broader version of my objection

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comment on wait so is 0.25 the "real" dose or is that just the starter in c/newbiequestions · 19 points · 2 days ago

counterpoint, some people do lose on the starter dose and then everyone tells them it's "just water weight" which is also kind of dismissive in the other direction

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comment on a pill with no food restrictions and no cold chain changes this entire site in c/orforglipron · -12 points · 2 days ago

speculating about a drug that is not on the market is exactly the content this site claims not to do

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comment on reta phase 2 was −24.2% at 48 weeks and people quote it like it is a maintenance number in c/retatrutide · -16 points · 2 days ago

everyone here already knows it is phase 2. this is a lecture.

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comment on PDF metadata says the file was created in a browser. is that normal? in c/coa · -21 points · 3 days ago

plenty of legitimate labs re-export to PDF. this whole post is vibes.

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comment on [Warning] wrong network. $180 gone. test with $5 first. in c/cryptopay · -12 points · 3 days ago

this is a wallet UX problem being described as a user problem

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comment on [Win] four denials, three appeals, one external review, approved in c/insurancefights · -12 points · 3 days ago

eleven months and three appeals is not a win

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comment on stretching the interval to 8 or 9 days instead of exactly 7 — smoothing tool or just messing with steady state in c/semaglutide · -13 points · 3 days ago

counterpoint, "the pharmacology says it's fine" is exactly the kind of reasoning that got people doing all sorts of things with these drugs that weren't actually tested, plausible math isn't the same as safety data

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comment on [Meta] should this community rename "maintenance phase" to something that doesn’t sound like an afterthought in c/maintenancephase · -9 points · 3 days ago

mild pushback, "maintenance" is a completely standard word in this exact context in the broader weight-management literature, not sure the community needs to reinvent terminology that already exists elsewhere

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comment on [PCOS] my androgens moved before my weight did and nobody had mentioned that was possible in c/glp1women · -11 points · 3 days ago

n=1 with no control and three confounders

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comment on [Pattern] the nine scams. that is it. there are only nine. in c/scamalerts · 47 points · 3 days ago

i have been trying for a year and the closest i got was a variant of three. annoying.

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comment on hair started shedding at month 4 and stopped at month 9. protein and patience. in c/sideeffects · -13 points · 3 days ago

three interventions, no control, self-limiting condition. this post cannot support any conclusion.

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comment on [Pattern] the nine scams. that is it. there are only nine. in c/scamalerts · -24 points · 3 days ago

a list of nine things is not a taxonomy, it is a list. this gets treated like scripture in here.

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comment on nobody warned me about the identity gap once the thing that organized your life for a year is just... gone in c/maintenancephase · -14 points · 3 days ago

counterpoint that might be unpopular: some of this "identity gap" talk risks romanticizing the disorder-adjacent obsessive tracking phase a little, losing that intensity might just be healthy, not a loss

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