appetite: the version I wish someone had shown me in week 1
Confession thread, sort of.
I went from 12.5mg to 5mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 10 weeks later, at which point I had no way of knowing whether the dose increase did anything or whether it would have broken anyway.
So now I have sulphur burps I did not need and a data point I cannot interpret. Two lessons in one.
Posting it in the hope that somebody at week 88 reads it before doing the same thing.
best — the order this archive was captured in
rodent appetite tells you what to investigate, not what to expect in humans
Disagree. What you are describing is consistent with mechanism, not with what you concluded.
This is correct. Rodent data is investigational, not predictive.
Is that mechanism or speculation?
amylin is not GLP-1, posts conflating them get corrected
Strongly agree. Central appetite is real but people overstate it.
Respectfully this is a sample of one presented as a finding.
glucagon-receptor contribution is incretin for dual and triple agonism
Yeah, the incretin mechanism is doing the work here.
Not convinced. The evidence does not support that reading.
rodent incretin tells you what to investigate, not what to expect in humans
rodent incretin tells you what to investigate, not what to expect in humans
Disagree on that part. 97.4% and 98.9% on the same vial is normal.
cite the paper: journal, year, first author, links optional
rodent mechanism tells you what to investigate, not what to expect in humans
[deleted]
This is correct. Rodent data is investigational, not predictive.
gastric emptying is real and explains most early constipation
the half-life is pharmacology, affects steady state timing
Is that mechanism or speculation?
glucagon-receptor contribution is gastric emptying for dual and triple agonism
Tracking number removed. It identifies both ends of a shipment.
- 1Not convinced. The evidence does not support that reading.9 comments in this branch · started by u/incretin_ivy
- 2This is correct. Rodent data is investigational, not predictive.4 comments in this branch · started by u/neha_krastev