reading phase 2 threads from 2024 and half of it aged badly
Trying to settle this properly because the thread from last year went in circles.
The claim: glucagon matters. The counter-claim: it is measurement error. Both sides have been asserting it confidently for about 7 months without either producing anything.
What would actually settle it is 5 people measuring the same thing the same way. I have started; my numbers are below. They lean one way but not strongly enough for me to declare victory.
If you have data, post the data. If you have an opinion, flair it as an opinion.
best — the order this archive was captured in
the 1.0mg arm is different from 2.4mg, results do not transfer
retatrutide is not approved anywhere for human use, posts must not read as instructions
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Adding to this: TRIUMPH is doing more work than the comment implies.
phase 2 numbers are not maintenance numbers, cite the trial
Not to be pedantic but phase 2 and glucagon are being used interchangeably and they are not interchangeable in real life.
the glucagon component changes the side effect profile, not just the efficacy
Yeah, phase 2 retatrutide is interesting but it is not comparable to phase 3 compounds.
That is net peptide content, not purity. Different number, different meaning.
the 0.25mg arm is different from 2.5mg, results do not transfer
This is correct. Triple agonism is genuinely different.
the glucagon component changes the side effect profile, not just the efficacy
That is net peptide content, not purity.
Yes, exactly this, and it is the bit that took me 88 weeks to accept.
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