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Single comment threadYou are looking at one branch of [Stats] the placebo arm lost weight too. always ask by how much. — 18 comments in the full submission. View in context.
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c/trialwatch·submitted 10 days ago by u/customs_seizure_sid

[Stats] the placebo arm lost weight too. always ask by how much.

Statsbranch of 5 comments

Right, the SURMOUNT question again, but with numbers this time. I have 4 data points over 24 weeks. The pattern is consistent enough that I do not think it is chance, and boring enough that nobody is going to screenshot it, which is usually a good sign. The thing I would flag for anyone new: the effect I am…

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5 comments, started 10 days ago
u/camila_vasquez44 points·10 days ago

Inter-lab variance on this kind of assay is routinely 1–2 points. Different column, different gradient, different integration.

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u/milan_mensah12 points·9 days ago

Mechanistically the bit that matters is SELECT. It explains most of the early profile and a decent chunk of the outcome.

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u/ines_boateng28 points·9 days ago

Is that absolute or relative risk reduction?

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u/customs_seizure_sidOP32 points·9 days ago

the discontinuation arms are the interesting part, not the SURPASS endpoints

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u/customs_seizure_sidOP18 points·9 days ago

absolute risk reduction, not relative risk reduction, that is how you decide

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