three years of SELECT threads, summarised so you do not have to read them
Right, the SURMOUNT question again, but with numbers this time. I have 2 data points over 30 weeks. The pattern is consistent enough that I do not think it is chance, and boring enough that nobody is going to screenshot it, which is usually a good sign. The thing I would flag for anyone new: the effect I am…
Yeah, absolute numbers matter more than the press release.
absolute risk reduction, not relative risk reduction, that is how you decide
number-needed-to-treat is the house dialect
off-label use data is different from approved-indication data
STEP 1 readout: 99.1% mean weight loss, absolute numbers matter. Spread around that mean is enormous.
the discontinuation arms are the interesting part, not the STEP endpoints