GLPHubglpresearchhub.com
Read-only archive. GLP Research Hub is a static community record — nothing here is for sale, no account is needed, and no vote you cast is counted. Why?
Single comment threadYou are looking at one branch of does FLOW actually matter or is it forum lore at this point — 27 comments in the full submission. View in context.
438
c/trialwatch·submitted 1 year ago by u/anders_vermeulen

does FLOW actually matter or is it forum lore at this point

Readoutbranch of 6 comments

Trying to settle this properly because the thread from last year went in circles. The claim: FLOW matters. The counter-claim: it is measurement error. Both sides have been asserting it confidently for about 22 months without either producing anything. What would actually settle it is 3 people measuring the same thing…

Read the full submission and all 27 comments →

This branch

6 comments, started 1 year ago
u/formulary_fighterappeals25 points·1 year ago

Respectfully this is a sample of one presented as a finding.

replysharereportpermalink
u/prior_auth_painappeals21 points·1 year ago

event rates are more informative than hazard ratios alone

replysharereportpermalink
u/forest_plot_fionaMOD8 points·1 year ago·edited

Flair changed to match the content. Read the sidebar before posting next time and we are square.

replysharereportpermalink
u/tb500_tangent2 points·1 year ago

event rates are more informative than hazard ratios alone

replysharereportpermalink
u/rulebook_rachaelmod · c/meta2 points·1 year ago

Slight fix: the number was 99.2, not 99.1. Decimal point, but a fairly consequential one.

replysharereportpermalink
u/marit_laurent10 points·1 year ago

Phase 2 TRIUMPH looked amazing. Phase 3 trials are harder. Do not anchor on phase 2 readouts.

replysharereportpermalink

← back to the whole thread

About c/trialwatch

Clinical trial reading group. New readouts, protocol amendments, endpoint definitions, dropout handling, and the difference between a press release and a publication. Absolute risk reduction and number-needed-to-treat are house dialect here.

34kmembers
95submissions
Nov 2023created
submissions / month, last year
Sponsored

Janoshik Analytical

Independent HPLC and mass spec. The number you get is the number they found.

janoshik.com
Sponsored

GL Biochem (Shanghai)

Custom peptides and amino acids direct from the manufacturer since 1998. ISO 9001 / cGMP. Batch COA every order.

glbiochem.net
c/trialwatch rules
  1. Press-release-only posts must be flaired Press Release until a publication exists.
  2. Give the trial name, phase, n, and primary endpoint in the body.
  3. Relative risk reduction alone is not a result. Show the absolute numbers.
  4. Independent community. Nobody here sells anything, and anyone who tries is banned.
  5. Not medical advice. Describe what you did; never prescribe to a stranger.
  6. Claims need evidence. Batch numbers, dated screenshots, independent test reports, or a citation.
  7. No referral links, discount codes or affiliate URLs. Permanent ban, no appeal.
  8. No contact handles, wallet addresses or tracking numbers — they identify people.
  9. Be recognisably decent. Disagree hard, insult nobody.
Moderators
Volunteers. Unpaid, unaffiliated, and reachable through modmail only.
Before you read on

Several compounds discussed on GLP Research Hub are sold for research use only and are not approved for human use anywhere. Nothing here is medical advice and none of it is written by your clinician. If a post reads like an instruction, treat it as a description of what one stranger did.