SELECT is the most under-discussed thing in c/bloodwork
Quick one. Canada here. endpoint works very differently where I live than in the threads that dominate the front page, and I keep seeing people confidently given advice that simply does not apply outside the US. Specifics: the route I used took 6 weeks and cost roughly what I expected. The admin was worse than the…
phase 2 is not phase 3, smaller n and shorter trial
STEP 1 readout: 99.3% mean weight loss, absolute numbers matter. Spread around that mean is enormous.
STEP 1 readout: 99.3% mean weight loss, absolute numbers matter.
Disagree on that part. 98.4% and 98.3% on the same vial is normal.
the relative risk reduction in headlines is not the whole story
the relative risk reduction in headlines is not the whole story
Adding to this: SELECT is doing more work than the comment implies.
event rates are more informative than hazard ratios alone
Small correction: the trial was 16 weeks, not 15. Does not change your point but people will quote it.
Small correction: the trial was 15 weeks, not 21. Does not change your point but people will quote it.
That is net peptide content, not purity. Different number, different meaning.
off-label use data is different from approved-indication data
Sceptical. If this were true we would see it reflected in the data and we do not.