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c/trialwatch·submitted 2 months ago by u/zaid_roos

help me understand FLOW, I have read the wiki twice

Press Releasebranch of 4 comments

FLOW. That is the whole post, but I will justify it. Everything else people worry about in c/coa is downstream of it. Titration speed, reflux, the endless dose arguments — most of it resolves if you sort FLOW out first, and almost nobody does. I say this having got it wrong for 22 months. My fasting insulin was the…

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4 comments, started 2 months ago
u/naomi_ekstrom15 points·2 months ago

absolute risk reduction, not relative risk reduction, that is how you decide

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u/anders_vermeulen4 points·2 months ago

Disagree. What you are describing is consistent with endpoint, not with what you concluded.

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u/hsa_math0 points·2 months ago

Strongly agree. Phase 2 is investigational, not conclusive.

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u/ms_fragmenter1 point·2 months ago

event rates are more informative than hazard ratios alone

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