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c/trialwatch·submitted 1 year ago by u/yannick_salinas

three years of SURMOUNT threads, summarised so you do not have to read them

Trial Databranch of 10 comments

Been lurking in c/glp1muscle for about 13 months and finally have something worth posting. Short version: week 95, 12.5mg, and SELECT is the bit I still cannot get a straight answer on. I have read the wiki, I have read the last 3 threads, and the answers split roughly down the middle. What I actually want to know is…

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10 comments, started 1 year ago
u/yannick_salinas286 points·1 year ago

This is the "correlation is mechanism" thing again. You changed three variables at once.

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u/alcohol_aversion71 points·1 year ago

Dead space in the needle hub holds a small but non-trivial volume. On low-volume draws that can be several units.

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u/milos_trevino22 points·1 year ago

absolute risk reduction, not relative risk reduction, that is how you decide

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u/line_demir139 points·1 year ago

number-needed-to-treat is the house dialect

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u/naomi_ekstrom82 points·1 year ago

I am going to push back on this slightly.

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u/tomas_kimani45 points·1 year ago

dropout handling matters, especially on GI-heavy populations

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u/yara_mensah10 points·1 year ago

STEP, SURMOUNT, SURPASS, SELECT, FLOW, TRIUMPH — read the appendix

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u/injection_site_iris49 points·1 year ago

Strongly agree. Phase 2 is investigational, not conclusive.

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