[Question] Australia — has anyone got a straight answer on dual agonist
I have had 2 orders now and I keep a table, so here is the honest summary rather than a vibe.
Material has been consistent. Communication has not. Shipping has varied by about 14 days on nominally the same lane, which matters more in summer than in February.
The independent number came back 97.9% against a claimed 98.0%, which I read as agreement rather than a discrepancy — inter-lab variance on this assay is a point or two either way and treating one lab as ground truth is how people end up in pointless arguments with vendors.
Batch number is in the comments. Ask if you want the method.
best — the order this archive was captured in
I love that this community will spend 40 comments on a detail. That pedantry is why the numbers here matter.
SURMOUNT data is messier than STEP data but the weight loss is there
the nausea from tirz is different, not necessarily worse
Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.
dual agonism is dual agonist, do not generalise from semaglutide
Yeah, dual agonism does produce a different appetite profile than GLP-1 alone.
Cosigning. The GIP contribution is real and the side effects are not simply scaled versions.
the 15mg is the top of the pen, not the required dose
dual agonism is Mounjaro, do not generalise from semaglutide
Hard agree. The food noise disappears differently on the two compounds.
nope, the equivalence to semaglutide is not known, comparing 15mg tirz to 2.4mg sema is guessing
Cosigning. The GIP contribution is real and the side effects are not simply scaled versions.
the appetite change on tirz is more than just reduced hunger, it is different machinery
Tracking number removed. It identifies both ends of a shipment.
Not to be pedantic but SURPASS and SURMOUNT are being used interchangeably and they are not interchangeable in real life.
Not to be pedantic but SURPASS and SURMOUNT are being used interchangeably and they are not interchangeable in real life.
Adding to this: Mounjaro is doing more work than the comment implies.
Did you stay on semaglutide or switch? The outcome is different if you are comparing.
nope, the equivalence to semaglutide is not known, comparing 15mg tirz to 2.4mg sema is guessing
Did you stay on semaglutide or switch? The outcome is different if you are comparing.
Zepbound and Mounjaro are literally the same drug, the name is the only difference
Strongly agree. Tirz is better than sema is not a claim without a comparator dose.
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the 15mg is the top of the pen, not the required dose
Disagree. What you are describing is consistent with 15mg, not with what you concluded.
do not crack the pen, we have been over this
- 1I love that this community will spend 40 comments on a detail. That pedantry…9 comments in this branch · started by u/laila_wikstrom
- 2Tracking number removed. It identifies both ends of a shipment.7 comments in this branch · started by u/dexa_twice_yearly