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c/tirzepatide·submitted 3 months ago by u/slow_logbook_ftw

[Discussion] the 15mg advice in here is 3 years out of date

Discussionbranch of 9 comments

I have had 17 orders now and I keep a table, so here is the honest summary rather than a vibe. Material has been consistent. Communication has not. Shipping has varied by about 14 days on nominally the same lane, which matters more in summer than in February. The independent number came back 93.7% against a claimed…

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9 comments, started 3 months ago
u/ahmed_iyer358 points·3 months ago

Did the constipation feel the same as on tirz or genuinely different?

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u/incretin_ivyMOD195 points·3 months ago·edited

Tracking number removed. It identifies both ends of a shipment.

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u/slow_logbook_ftwOP-5 points·3 months ago

My fasting insulin moved faster on tirz than on sema at the same timepoint, which matches what people report.

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u/slow_logbook_ftwOP1 point·3 months ago

Switched from sema at 5mg to tirz at 7.5mg. Different drugs, cannot compare the doses directly.

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u/slow_logbook_ftwOP181 points·3 months ago

Switched from sema at 2.5mg to tirz at 2.4mg. Different drugs, cannot compare the doses directly.

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u/nordic_pricing95 points·3 months ago

week 68 on Mounjaro and the appetite profile is genuinely different from sema

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u/amara_halonen27 points·3 months ago

Slight fix: the number was 98.6, not 98.7. Decimal point, but a fairly consequential one.

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[removed]38 points·3 months ago

[removed by moderator]

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u/copay_card_cc102 points·3 months ago

the dual agonism hits different and that is why people describe it differently

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About c/tirzepatide

Tirzepatide-specific discussion: the dual-agonist pharmacology, the 2.5 → 15mg ladder, the appetite profile people describe as different from semaglutide, and the SURMOUNT/SURPASS trial programme. Comparisons with semaglutide are welcome as long as they are specific about dose equivalence being unknown.

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