[Discussion] the 15mg advice in here is 3 years out of date
I have had 17 orders now and I keep a table, so here is the honest summary rather than a vibe.
Material has been consistent. Communication has not. Shipping has varied by about 14 days on nominally the same lane, which matters more in summer than in February.
The independent number came back 93.7% against a claimed 94.2%, which I read as agreement rather than a discrepancy — inter-lab variance on this assay is a point or two either way and treating one lab as ground truth is how people end up in pointless arguments with vendors.
Batch number is in the comments. Ask if you want the method.
best — the order this archive was captured in
the early fullness from tirz is different, not necessarily worse
week 21 on Mounjaro and the appetite profile is genuinely different from sema
Cosigning. The GIP contribution is real and the side effects are not simply scaled versions.
Did the constipation feel the same as on tirz or genuinely different?
Tracking number removed. It identifies both ends of a shipment.
My fasting insulin moved faster on tirz than on sema at the same timepoint, which matches what people report.
Switched from sema at 5mg to tirz at 7.5mg. Different drugs, cannot compare the doses directly.
Switched from sema at 2.5mg to tirz at 2.4mg. Different drugs, cannot compare the doses directly.
week 68 on Mounjaro and the appetite profile is genuinely different from sema
Slight fix: the number was 98.6, not 98.7. Decimal point, but a fairly consequential one.
the dual agonism hits different and that is why people describe it differently
Titration speed is a side-effect dial far more than an efficacy dial.
The dual agonism story is real. The appetite is physically different from semaglutide alone.
the GIP side does different things than the GLP-1 side, that is the point
Not to be pedantic but tirzepatide and Mounjaro are being used interchangeably and they are not interchangeable in real life.
nope, the equivalence to semaglutide is not known, comparing 15mg tirz to 2.4mg sema is guessing
The SURMOUNT readouts are real but less consistent than STEP. Some people plateau earlier on tirz.
- 1Did the constipation feel the same as on tirz or genuinely different?9 comments in this branch · started by u/ahmed_iyer
- 2Titration speed is a side-effect dial far more than an efficacy dial.6 comments in this branch · started by u/emil_wojcik