[Discussion] GIP is doing more work than we give it credit for
Week 32 update. 28kg down from the start, early fullness basically gone since about week 84.
Things that worked: consistency, protein at breakfast, walking more than I want to. Things that did not: everything I bought on the internet to help with early fullness.
The part that surprised me is how much of this is admin. Ordering, storing, logging, remembering. Nobody mentions that the hard bit is not the drug, it is the routine.
Happy to answer anything. Please do not ask me what dose you should be on.
best — the order this archive was captured in
What was the trial arm you are quoting from? SURMOUNT-1, -2, -3 are all different.
the GIP side does different things than the GLP-1 side, that is the point
the nausea from tirz is different, not necessarily worse
nope, the equivalence to semaglutide is not known, comparing 15mg tirz to 2.4mg sema is guessing
My ALT moved faster on tirz than on sema at the same timepoint, which matches what people report.
Switched from sema at 1.0mg to tirz at 1.7mg. Different drugs, cannot compare the doses directly.
Did the nausea feel the same as on tirz or genuinely different?
How long at each step before you escalated?
The practical rule people converge on is 28 days at fridge temperature after first puncture, and that comes from the preservative, not the peptide.
Cosigning. The GIP contribution is real and the side effects are not simply scaled versions.
You have restated the marketing copy. What is the actual substance here.
Removed a chain here. The rule is one line long and it is not negotiable.
What was the trial arm you are quoting from? SURMOUNT-1, -2, -3 are all different.
My fasting insulin moved faster on tirz than on sema at the same timepoint, which matches what people report.
nope, the equivalence to semaglutide is not known, comparing 15mg tirz to 2.4mg sema is guessing
Removed a chain here.
Disagree on that part. 98.1% and 98.9% on the same vial is normal.
the dual agonism hits different and that is why people describe it differently
Zepbound and Mounjaro are literally the same drug, the name is the only difference
Hard agree. The food noise disappears differently on the two compounds.
- 1Removed a chain here. The rule is one line long and it is not negotiable.8 comments in this branch · started by u/quiet_moderator