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c/tirzepatide·posted 2 years ago by u/mod_cold_room

[Question] Poland — has anyone got a straight answer on dual agonist

Question Long Haul ×4 Cold Box ×2

Right, the SURPASS question again, but with numbers this time.

I have 24 data points over 12 weeks. The pattern is consistent enough that I do not think it is chance, and boring enough that nobody is going to screenshot it, which is usually a good sign.

The thing I would flag for anyone new: the effect I am describing showed up at week 79, not week 33. People give up long before the interesting part.

Interested in whether this matches other people's logs or whether I am an outlier.

3,038 up / 945 down76% upvoted19 commentsid 15e5st26 Oct 2023

19 comments

3 in this archive, depth 2

best — the order this archive was captured in

u/dario_stanescu170 points·2 years ago

Inter-lab variance on this kind of assay is routinely 1–2 points. Different column, different gradient, different integration.

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u/gentle_correctionnice about it100 points·2 years ago

Hard agree. The food noise disappears differently on the two compounds.

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u/sofia_nascimento79 points·2 years ago

dual agonism is GIP, do not generalise from semaglutide

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About c/tirzepatide

Tirzepatide-specific discussion: the dual-agonist pharmacology, the 2.5 → 15mg ladder, the appetite profile people describe as different from semaglutide, and the SURMOUNT/SURPASS trial programme. Comparisons with semaglutide are welcome as long as they are specific about dose equivalence being unknown.

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