small win: GIP stopped being a problem at week 81
Week 24 update. 25kg down from the start, reflux basically gone since about week 76.
Things that worked: consistency, protein at breakfast, walking more than I want to. Things that did not: everything I bought on the internet to help with reflux.
The part that surprised me is how much of this is admin. Ordering, storing, logging, remembering. Nobody mentions that the hard bit is not the drug, it is the routine.
Happy to answer anything. Please do not ask me what dose you should be on.
best — the order this archive was captured in
Strongly agree. Tirz is better than sema is not a claim without a comparator dose.
Cosigning. The GIP contribution is real and the side effects are not simply scaled versions.
that is the funniest sentence i have read on this site
Adding to this: Mounjaro is doing more work than the comment implies.
Zepbound and Mounjaro are literally the same drug, the name is the only difference
Strongly agree. Tirz is better than sema is not a claim without a comparator dose.
Strongly agree.
Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.
do not crack the pen, we have been over this
Zepbound and Mounjaro are literally the same drug, the name is the only difference
Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.
dual agonism is GIP, do not generalise from semaglutide
My triglycerides moved faster on tirz than on sema at the same timepoint, which matches what people report.
Inter-lab variance on this kind of assay is routinely 1–2 points. Different column, different gradient, different integration.
the dual agonism hits different and that is why people describe it differently
This is the "correlation is mechanism" thing again. You changed three variables at once.
You have restated the marketing copy. What is the actual substance here.
the 15mg is the top of the pen, not the required dose
The confident tone is doing a lot of work that the evidence is not.
the appetite change on tirz is more than just reduced hunger, it is different machinery
The confident tone is doing a lot of work that the evidence is not.
Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.
the 15mg is the top of the pen, not the required dose
nope, the equivalence to semaglutide is not known, comparing 15mg tirz to 2.4mg sema is guessing
- 1that is the funniest sentence i have read on this site10 comments in this branch · started by u/elin_ferrari
- 2My triglycerides moved faster on tirz than on sema at the same timepoint,…4 comments in this branch · started by u/hub_ops