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c/t2dglp1·submitted 1 months ago by u/nadia_norgaard

[Meta] the hypoglycaemia rule is doing its job and people should stop complaining

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Posting this because I searched for it and got nothing useful. Setup: 1.0mg, week 18, injection-site soreness present but not ruining anything. I changed exactly one variable — glycaemic control — and tracked it for 17 weeks. Result: a difference, but a small one, and well inside what I would call noise if someone…

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7 comments, started 1 months ago
u/arne_amankwah15 points·1 months ago

type 2 is the indication, weight loss is the side effect

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u/niels_salinas8 points·1 months ago

The confident tone is doing a lot of work that the evidence is not.

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u/sanne_laurent4 points·1 months ago

CGM traces tell a story, numbers alone do not

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u/kian_verhoeven1 point·1 months ago

CGM traces tell a story, numbers alone do not

Yes, exactly this, and it is the bit that took me 73 weeks to accept.

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u/a1c_arcT2D6 points·1 months ago

hypoglycaemia risk when stacked with A1c

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u/georgi_haddad7 points·1 months ago

type 2 is the indication, weight loss is the side effect

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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Type 2 diabetes as the original indication: A1c trajectories, CGM traces, hypoglycaemia risk when stacked with sulfonylureas or insulin, metformin combinations, and why the weight-loss conversation sometimes drowns out the glycaemic one.

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