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c/t2dglp1·submitted 2 years ago by u/nhs_waitlist_n

T2D vs metformin — genuinely asking which matters more

Discussionbranch of 5 comments

hypoglycaemia. That is the whole post, but I will justify it. Everything else people worry about in c/meta is downstream of it. Titration speed, reflux, the endless dose arguments — most of it resolves if you sort hypoglycaemia out first, and almost nobody does. I say this having got it wrong for 6 months. My fasting…

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5 comments, started 2 years ago
u/santiago_rasmussen21 points·2 years ago

the 30 A1c trend is the answer

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u/marisol_moreau5 points·2 years ago

Half-life is about 168 hours, so steady state lands around week 2–5. Practical consequence: what you feel in week 1 is not what that dose does.

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u/appeal_letter_al4 points·2 years ago

type 2 is the indication, weight loss is the side effect

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u/nhs_waitlist_nOPUK2 points·2 years ago

the 35 A1c trend is the answer

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u/cloudy_vial_carol7 points·2 years ago

no medication-stopping advice, ever

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Type 2 diabetes as the original indication: A1c trajectories, CGM traces, hypoglycaemia risk when stacked with sulfonylureas or insulin, metformin combinations, and why the weight-loss conversation sometimes drowns out the glycaemic one.

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