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c/retatrutide·submitted 5 months ago by u/placebo_arm_pam

why does nobody talk about triple agonist

Resultsbranch of 6 comments

Quick one. Canada here. glucagon works very differently where I live than in the threads that dominate the front page, and I keep seeing people confidently given advice that simply does not apply outside the US. Specifics: the route I used took 7 weeks and cost roughly what I expected. The admin was worse than the…

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6 comments, started 5 months ago
u/incretin_ivypharmacology197 points·5 months ago

phase 2 numbers are not maintenance numbers, cite the trial

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u/placebo_arm_pamOP0 points·5 months ago

TRIUMPH phase 2 showed 98.6% weight loss but the injection-site soreness profile on the highest arm was rough. Phase 2 != phase 3.

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u/ewan_zielinski1 point·5 months ago

phase 2 numbers are not maintenance numbers, cite the trial

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u/titration_marshalmod · c/semaglutide0 points·5 months ago

Yeah, phase 2 retatrutide is interesting but it is not comparable to phase 3 compounds.

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u/reta_and_regretMOD139 points·5 months ago

Flair changed to match the content. Read the sidebar before posting next time and we are square.

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u/clara_weiss76 points·5 months ago

Not to be pedantic but dose escalation and retatrutide are being used interchangeably and they are not interchangeable in real life.

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About c/retatrutide

Retatrutide: GIP/GLP-1/glucagon triple agonism, the TRIUMPH programme, and the fact that most people discussing it are handling research-grade material with no human-use approval anywhere. Dose-response, heart-rate signal, and the unusually steep phase-2 weight curves get argued about here weekly.

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  1. Retatrutide is not approved anywhere for human use. Posts must not read as usage instructions.
  2. Phase 2 numbers are not maintenance numbers. Cite the trial and the dose arm.
  3. Heart-rate and dose-escalation reports need actual measurements, not impressions.
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