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c/retatrutide·submitted 2 months ago by u/clara_weiss

small win: dose escalation stopped being a problem at week 95

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Confession thread, sort of. I went from 10mg to 2.5mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 8 weeks later, at which point I had no way of knowing whether the dose increase did anything or whether it would have broken anyway. So now I have…

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4 comments, started 2 months ago
u/incretin_ivyMOD12 points·2 months ago

This is an urgent-care question wearing a forum question's clothes. Please contact a clinician rather than waiting for replies.

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u/clara_weissOP6 points·2 months ago

This is correct. Triple agonism is genuinely different.

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u/devils_advocate_d10 points·2 months ago

the dosing is steep, the sulphur burps reports are real, and nobody knows the human safety yet

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u/two_mil_or_one8 points·2 months ago·edited

TRIUMPH data is phase 2, not phase 3, smaller n and shorter

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About c/retatrutide

Retatrutide: GIP/GLP-1/glucagon triple agonism, the TRIUMPH programme, and the fact that most people discussing it are handling research-grade material with no human-use approval anywhere. Dose-response, heart-rate signal, and the unusually steep phase-2 weight curves get argued about here weekly.

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