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crossposted from c/t2dglp1 by u/emil_okwuosa — [Question] Australia — has anyone got a straight answer on metformin

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c/retatrutide·posted 7 months ago by u/emil_wojcik

[Question] how do you actually verify TRIUMPH

Question Well Actually ×8 Slow Clap ×3

Right, the triple agonist question again, but with numbers this time.

I have 14 data points over 8 weeks. The pattern is consistent enough that I do not think it is chance, and boring enough that nobody is going to screenshot it, which is usually a good sign.

The thing I would flag for anyone new: the effect I am describing showed up at week 62, not week 16. People give up long before the interesting part.

Interested in whether this matches other people's logs or whether I am an outlier.

1,588 up / 311 down84% upvoted44 commentsid vmzdg922 Dec 2025

44 comments

6 in this archive, depth 4sorted by:

best — the order this archive was captured in

u/discount_math_dm163 points·7 months ago

Research use material only, no human-use approval anywhere. Posts must describe what happened, not instruct strangers.

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u/ismael_eriksen81 points·7 months ago

research use only, handling and analysis, not protocols

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u/reta_and_regretMOD42 points·7 months ago

Removed a chain here. The rule is one line long and it is not negotiable.

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u/andres_sorensen13 points·7 months ago

Removed a chain here.

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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u/soren_nkemelu4 points·7 months ago

TRIUMPH data is phase 2, not phase 3, smaller n and shorter

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u/trialwatch_theotrial nerd10 points·7 months ago

Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.

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1research use only, handling and analysis, not protocols5 comments in this branch · started by u/ismael_eriksen

Deep branches get their own page so a single reply chain can be linked and read on its own.

About c/retatrutide

Retatrutide: GIP/GLP-1/glucagon triple agonism, the TRIUMPH programme, and the fact that most people discussing it are handling research-grade material with no human-use approval anywhere. Dose-response, heart-rate signal, and the unusually steep phase-2 weight curves get argued about here weekly.

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Janoshik Analytical

Independent HPLC and mass spec. The number you get is the number they found.

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More in c/retatrutide

1[Results] 2 weeks, 46kg, and phase 2 was the hard part14k points · 45 comments
2switched from 2.5mg to 10mg and the early fullness got better, not worse13k points · 37 comments
3glucagon — my 7-week log, condensed into one table12k points · 37 comments
4what changed for me between week 65 and week 1312k points · 35 comments
5[Results] 37 weeks, 16kg, and phase 2 was the hard part9.9k points · 50 comments
6unpopular opinion: retatrutide is massively overrated8.7k points · 68 comments

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