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Single comment threadYou are looking at one branch of what changed for me between week 65 and week 13 — 35 comments in the full submission. View in context.
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c/retatrutide·submitted 2 years ago by u/reflux_report

what changed for me between week 65 and week 13

Trial Databranch of 6 comments

I have had 9 orders now and I keep a table, so here is the honest summary rather than a vibe. Material has been consistent. Communication has not. Shipping has varied by about 40 days on nominally the same lane, which matters more in summer than in February. The independent number came back 97.9% against a claimed…

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6 comments, started 2 years ago
u/employer_carveout682 points·2 years ago

Every time this gets posted it hits the front page and every time someone has to re-explain it.

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u/niels_lindqvist390 points·2 years ago

Disagree but this is the good kind of wrong — it is specific enough to be checked.

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u/hassan_nilsen287 points·2 years ago

phase 2 numbers are not maintenance numbers, cite the trial

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u/source_or_silence195 points·2 years ago

triple agonism is phase 2, do not generalise

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u/naomi_erdogan131 points·2 years ago·edited

the glucagon component changes the side effect profile, not just the efficacy

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u/careful_gradient32370 points·2 years ago

triple agonism is glucagon, do not generalise

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About c/retatrutide

Retatrutide: GIP/GLP-1/glucagon triple agonism, the TRIUMPH programme, and the fact that most people discussing it are handling research-grade material with no human-use approval anywhere. Dose-response, heart-rate signal, and the unusually steep phase-2 weight curves get argued about here weekly.

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