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Single comment threadYou are looking at one branch of tried phase 2 for 12 weeks. here is what happened. — 23 comments in the full submission. View in context.
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c/retatrutide·submitted 1 year ago by u/renzo_yildiz

tried phase 2 for 12 weeks. here is what happened.

Questionbranch of 6 comments

Right, the triple agonist question again, but with numbers this time. I have 11 data points over 38 weeks. The pattern is consistent enough that I do not think it is chance, and boring enough that nobody is going to screenshot it, which is usually a good sign. The thing I would flag for anyone new: the effect I am…

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6 comments, started 1 year ago
u/aa_analysis_andy23 points·1 year ago

Titration speed is a side-effect dial far more than an efficacy dial.

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u/cormac_roos6 points·1 year ago

the dosing is steep, the sulphur burps reports are real, and nobody knows the human safety yet

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u/renzo_yildizOP10 points·1 year ago

Are you quoting phase 2 or is there phase 3 data now?

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u/marit_laurent19 points·1 year ago

Sceptical. If this were true we would see it reflected in the data and we do not.

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u/renzo_yildizOP15 points·1 year ago

heart rate and dose escalation need actual measurements, not impressions

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u/rosa_almeida7 points·1 year ago·edited

the 2.5mg arm is different from 5mg, results do not transfer

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About c/retatrutide

Retatrutide: GIP/GLP-1/glucagon triple agonism, the TRIUMPH programme, and the fact that most people discussing it are handling research-grade material with no human-use approval anywhere. Dose-response, heart-rate signal, and the unusually steep phase-2 weight curves get argued about here weekly.

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