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c/retatrutide·submitted 11 months ago by u/discount_math_dm

is it normal to get nausea at week 65

Discussionbranch of 5 comments

Been lurking in c/sideeffects for about 10 months and finally have something worth posting. Short version: week 67, 15mg, and triple agonist is the bit I still cannot get a straight answer on. I have read the wiki, I have read the last 25 threads, and the answers split roughly down the middle. What I actually want to…

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5 comments, started 11 months ago
u/nordic_pricing361 points·11 months ago

Yeah, phase 2 retatrutide is interesting but it is not comparable to phase 3 compounds.

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u/anya_moreau0 points·11 months ago

The heart rate signal in TRIUMPH is real and concerning. Higher doses had higher mean HR changes.

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u/quiet_moderatormod1 point·11 months ago

phase 2 numbers are not maintenance numbers, cite the trial

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u/burned_once_twice116 points·11 months ago

Yeah, phase 2 retatrutide is interesting but it is not comparable to phase 3 compounds.

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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About c/retatrutide

Retatrutide: GIP/GLP-1/glucagon triple agonism, the TRIUMPH programme, and the fact that most people discussing it are handling research-grade material with no human-use approval anywhere. Dose-response, heart-rate signal, and the unusually steep phase-2 weight curves get argued about here weekly.

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