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c/orforglipron·posted 1 year ago by u/lukas_delgado

[Vendor] WXT order #24 — Germany, 35 days, no drama, receipts inside

Discussion Receipts ×3

Quick one. Canada here.

small molecule works very differently where I live than in the threads that dominate the front page, and I keep seeing people confidently given advice that simply does not apply outside the US.

Specifics: the route I used took 3 weeks and cost roughly what I expected. The admin was worse than the cost. The thing that would have saved me the most time was knowing which document to ask for at the start.

Happy to answer questions from anyone in the same jurisdiction.

996 up / 165 down86% upvoted46 commentsid 2v1oyf27 Apr 2025

46 comments

28 in this archive, depth 5

best — the order this archive was captured in

u/farid_kuipers100 points·1 year ago

This is correct. ATTAIN data is phase 3.

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u/trialwatch_theotrial nerd31 points·1 year ago

Not to be pedantic but oral GLP-1 and small molecule are being used interchangeably and they are not interchangeable in real life.

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u/whois_wanda27 points·1 year ago·edited

How many weeks between the two measurements?

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u/neha_rahimi59 points·1 year ago

Dead space in the needle hub holds a small but non-trivial volume. On low-volume draws that can be several units.

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u/farid_kuipers85 points·1 year ago

That is net peptide content, not purity. Different number, different meaning.

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u/greta_nilsen70 points·1 year ago

availability speculation must be flaired Speculation

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[removed]24 points·1 year ago

[removed by moderator]

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u/certified_referenceQC20 points·1 year ago

no cold chain means ATTAIN, if approved

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u/maren_sorensen49 points·1 year ago

Water content matters more than people think. If a vial is carrying residual moisture, your "10mg" is not 10mg of peptide.

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u/search_before_post20 points·1 year ago

That is net peptide content, not purity. Different number, different meaning.

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u/maren_sorensen13 points·1 year ago

This is the "correlation is mechanism" thing again. You changed three variables at once.

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u/enzo_ferrari9 points·1 year ago

small molecule purity is different testing than peptides

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u/kenji_kimani-31 points·1 year ago

Did anything else change in the same window?

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u/emeka_delgado7 points·1 year ago

cite ATTAIN/ACHIEVE arms specifically

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u/lina_bruun7 points·1 year ago

Not to be pedantic but ACHIEVE and orforglipron are being used interchangeably and they are not interchangeable in real life.

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u/sofia_petrescu5 points·1 year ago

Small correction: the trial was 19 weeks, not 27. Does not change your point but people will quote it.

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u/lukas_delgadoOP4 points·1 year ago

What are you comparing it against though?

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u/lina_novak0 points·1 year ago

oral non-peptide agonist is non-peptide, no food restrictions

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u/trialwatch_theoMOD31 points·1 year ago

This is an urgent-care question wearing a forum question's clothes. Please contact a clinician rather than waiting for replies.

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u/ewan_hovland7 points·1 year ago

What are you comparing it against though?

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u/canada_coverage15 points·1 year ago

Yeah, small molecule changes the whole game.

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u/lina_bruun17 points·1 year ago

Slight fix: the number was 98.7, not 98.1. Decimal point, but a fairly consequential one.

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u/zeynep_ndiaye10 points·1 year ago

small molecule, not a peptide, purity discussion is different

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u/lucia_bruun13 points·1 year ago

availability speculation must be flaired Speculation

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u/dario_boateng9 points·1 year ago

The confident tone is doing a lot of work that the evidence is not.

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u/ines_lindqvist19 points·1 year ago

The practical rule people converge on is 28 days at fridge temperature after first puncture, and that comes from the preservative, not the peptide.

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u/joaquin_trevino13 points·1 year ago

This is correct. ATTAIN data is phase 22.

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u/emil_marchand3 points·1 year ago

phase 15 data is interesting, phase 10 will tell the real story

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The small-molecule oral: why a non-peptide agonist escapes the absorption problems of oral semaglutide, what the ATTAIN and ACHIEVE readouts showed, and what a pill with no refrigeration requirement would do to the entire supply conversation this site is built around.

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